TCDB is operated by the Saier Lab Bioinformatics Group
SSEARCH:
Description: Perform a sequence similarity search against TC-DB with a query protein. SSEARCH performs a rigorous Smith-Waterman local alignment between a protein and a protein database. SSEARCH employs an exhaustive algorithm whereas BLAST and FASTA use a heuristic methodology. As a consequence SSEARCH is slower in comparison to either BLAST or FASTA, however what you lose in speed is regained in sensitivity.
Expect Cutoff: Alignments: Matrix:
Gap Open Penalty: Gap Extension Penalty: Show Histogram:

Enter protein UniProt ID or FASTA sequence:

SSEARCH version 3.4t20 Nov 10, 2002
T. F. Smith and M. S. Waterman, (1981) J. Mol. Biol. 147:195-191
W.R. Pearson (1991) Genomics 11:635-650