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Family	Description	Abbreviation
1.A.1	The Voltage-gated Ion Channel (VIC) Superfamily	VIC
1.A.10	The Glutamate-gated Ion Channel (GIC) Family of Neurotransmitter Receptors	GIC
1.A.11	The Ammonia Transporter Channel (Amt) Family	Amt
1.A.12	The Intracellular Chloride Channel (CLIC) Family
1.A.13	The Epithelial Chloride Channel (E-ClC) Family	E-ClC
1.A.14	The Testis-Enhanced Gene Transfer (TEGT) Family	TEGT
1.A.15	The Non-selective Cation Channel-2 (NSCC2) Family	NSCC2
1.A.16	The Formate-Nitrite Transporter (FNT) Family	FNT
1.A.17	The Calcium-Dependent Chloride Channel (Ca-ClC) Family	CaClC
1.A.18	The Chloroplast Envelope Anion Channel-forming Tic110 (Tic110) Family	Tic110
1.A.19	The Type A Influenza Virus Matrix-2 Channel (M2-C) Family	M2-C
1.A.2	Inward Rectifier K⁺ Channel (IRK-C) Family	IRK-C
1.A.20	The BCL2/Adenovirus E1B-interacting Protein 3 (BNip3) Family	CytB
1.A.21	The Bcl-2 (Bcl-2) Family	Bcl-2
1.A.22	The Large Conductance Mechanosensitive Ion Channel (MscL) Family	MscL
1.A.23	The Small Conductance Mechanosensitive Ion Channel (MscS) Family	MscS
1.A.24	The Gap Junction-forming Connexin (Connexin) Family	Connexin
1.A.25	The Gap Junction-forming Innexin (Innexin) Family	Innexin
1.A.26	The Mg²⁺ Transporter-E (MgtE) Family	MgtE
1.A.27	The Phospholemman (PLM) Family	PLM
1.A.28	The Urea Transporter (UT) Family	UT
1.A.29	The Urea/Amide Channel (UAC) Family	UAC
1.A.3	The Ryanodine-Inositol 1,4,5-triphosphate Receptor Ca²⁺ Channel (RIR-CaC) Family
1.A.30	The H⁺- or Na⁺-translocating Bacterial Flagellar Motor/ExbBD Outer Membrane Transport Energizer (Mot/Exb) Superfamily	Mot/Exb
1.A.31	The Annexin (Annexin) Family	Annexin
1.A.32	The Type B Influenza Virus NB Channel (NB-C) Family	NB-C
1.A.33	The Cation Channel-forming Heat Shock Protein-70 (Hsp70) Family	Hsp70
1.A.34	1.A.34 The Bacillus Gap Junction-like Channel-forming Complex (GJ-CC) Family
1.A.35	The CorA Metal Ion Transporter (MIT) Family	MIT
1.A.36	The Intracellular Chloride Channel (ICC) Family	ICC
1.A.37	The CD20 Ca²⁺ Channel (CD20) Family	CD20
1.A.38	The Golgi pH Regulator (GPHR) Family
1.A.39	The Type C Influenza Virus CM2 Channel (CM2-C) Family	CM2-C
1.A.4	The Transient Receptor Potential Ca²⁺ Channel (TRP-CC) Family	TRP-CC
1.A.40	The Human Immunodeficiency Virus Type I, HIV-1 (Retrovirdiac) Vpu Channel (Vpu-C) Family	Vpu-C
1.A.41	The Avian Reovirus p10 Viroporin (p10) Family	p10
1.A.42	The HIV Viral Protein R (Vpr) Family	Vpr
1.A.43	The PRD1 Phage DNA Delivery (PRD1-DD) Family	PRD1-DD
1.A.44	The Pore-forming Tail Tip pb2 Protein of Phage T5 (T5-pb2) Family	T5-pb2
1.A.45	The Phage P22 Injectisome (P22 Injectisome) Family
1.A.46	The Anion Channel-forming Bestrophin (Bestrophin) Family	Bestrophin
1.A.47	The Nucleotide-sensitive Anion-selective Channel, ICln (ICln) Family	ICln
1.A.48	The Anion Channel Tweety (Tweety) Family
1.A.49	The Mitochondrial Ca²⁺ Uniport Channel (MICC) Family	MICC
1.A.5	The Polycystin Cation Channel (PCC) Family	PCC
1.A.50	The Phospholamban (Ca²⁺-channel and Ca²⁺-ATPase Regulator) (PLB) Family	PLB
1.A.51	The Voltage-gated Proton Channel (VPC) Family	VPC
1.A.52	The Ca²⁺ Release-activated Ca²⁺ (CRAC) Channel (CRAC-C) Family
1.A.53	The Hepatitis C Virus P7 Viroporin Cation-selective Channel (HCV-P7) Family
1.A.54	The Presenilin ER Ca²⁺ Leak Channel (Presenilin) Family
1.A.55	The Synaptic Vesicle-Associated Ca²⁺ Channel, Flower (Flower or Cg6151-p) Family
1.A.56	The Copper Transporter (Ctr) Family
1.A.57	The Human SARS Caronavirus Viroporin (SARS-VP)	SARS-VP
1.A.58	The Type B Influenza Virus Matrix Protein 2 (BM2-C) Family
1.A.59	The Bursal Disease Virus Pore-Forming Peptide, Pep46 (Pep46) Family
1.A.6	The Epithelial Na⁺ Channel (ENaC) Family	ENaC
1.A.60	The Mammalian Reovirus Pre-forming Peptide, Mu-1 (Mu-1) Family
1.A.61	The Insect Nodavirus Channel-forming Chain F (Gamma-Peptide) Family
1.A.62	The Homotrimeric Cation Channel (TRIC) Family
1.A.63	The Ignicoccus Outer Membrane α-helical Porin Family
1.A.64	The Plasmolipin (Plasmolipin) Family
1.A.65	The Coronavirus Viroporin E Protein (Viroporin E) Family
1.A.66	The Pardaxin (Pardaxin) Family
1.A.67	The Membrane Mg²⁺ Transporter (MMgT) Family	MMgT
1.A.68	The Viral Small Hydrophobic Protein (V-SHP) Family
1.A.69	The Heteromeric Odorant Receptor Channel (HORC) Family
1.A.7	The ATP-gated P2X Receptor Cation Channel (P2X Receptor) Family
1.A.70	The Molecule Against Microbes A (MamA) Family
1.A.71	The Brain Acid-soluble Protein Channel (BASP1 Channel) Family
1.A.72	The Mer Superfamily	MER
1.A.73	The Colicin Lysis Protein (CLP) Family	CLP
1.A.74	The Mitsugumin 23 (MG23) Family	MG23
1.A.75	The Mechanical Nociceptor, Piezo (Piezo) Family
1.A.76	The Mitochondrial EF Hand Ca²⁺ Uptake Porter/Regulator (MICU) Family	MICU
1.A.77	The Mg²⁺/Ca²⁺ Uniporter (MCU) Family	MCU
1.A.78	Classical Swine Fever Virus p7 Viroporin (CSFV-P7 Viroporin) Family	CSFV-P7 Viroporin
1.A.79	The Cholesterol Uptake Protein (ChUP) or Double Stranded RNA Uptake Family	dsRNA-T
1.A.8	The Major Intrinsic Protein (MIP) Family	MIP
1.A.80	The NS4a Viroportin (NS4a) Family	NS4a
1.A.81	The Low Affinity Ca²⁺ Channel (LACC) Family
1.A.82	The Hair Cell Mechanotransduction Channel (HCMC) Family	HCMC
1.A.83	The SV40 Virus Viroporin VP2 (SV40 VP2) Family	SV40 VP2
1.A.84	The Calcium Homeostasis Modulator Ca²⁺ Channel (CALHM-c) Family	CALHM-c
1.A.85	The Poliovirus 2B Viroporin (2B Viroporin) Family	2B Viroporin
1.A.86	The Human Papilloma Virus type 16 (HPV16) L2 Viroporin (L2 Viroporin) Family	L2 Viroporin
1.A.87	The Mechanosensitive Calcium Channel (MCA) Family	MCA
1.A.9	The Neurotransmitter Receptor, Cys loop, Ligand-gated Ion Channel (LIC) Family	LIC
1.B.1	The General Bacterial Porin (GBP) Family	GBP
1.B.10	The Nucleoside-specific Channel-forming Outer Membrane Porin (Tsx) Family	Tsx
1.B.11	The Outer Membrane Fimbrial Usher Porin (FUP) Family	FUP
1.B.12	The Autotransporter-1 (AT-1) Family	AT
1.B.13	The Alginate Export Porin (AEP) Family	AEP
1.B.14	The Outer Membrane Receptor (OMR) Family	OMR
1.B.15	The Raffinose Porin (RafY) Family	RafY
1.B.16	The Short Chain Amide and Urea Porin (SAP) Family	SAP
1.B.17	The Outer Membrane Factor (OMF) Family	OMF
1.B.18	The Outer Membrane Auxiliary (OMA) Protein Family	OMA
1.B.19	The Glucose-selective OprB Porin (OprB) Family	OprB
1.B.2	The Chlamydial Porin (CP) Family	CP
1.B.20	The Two-Partner Secretion (TPS) Family	TPS
1.B.21	The OmpG Porin (OmpG) Family
1.B.22	The Outer Bacterial Membrane Secretin (Secretin) Family	Secretin
1.B.23	The Cyanobacterial Porin (CBP) Family	CBP
1.B.24	The Mycobacterial Porin (MBP) Family	MBP
1.B.25	The Outer Membrane Porin (Opr) Family	OPr
1.B.26	The Cyclodextrin Porin (CDP) Family	CDP
1.B.27	The Helicobacter Outer Membrane Porin (HOP) Family	HOP
1.B.28	The Plastid Outer Envelope Porin of 24 kDa (OEP24) Family	OEP24
1.B.29	The Plastid Outer Envelope Porin of 21 kDa (OEP21) Family	OEP21
1.B.3	The Sugar Porin (SP) Family	SP
1.B.30	The Plastid Outer Envelope Porin of 16 kDa (OEP16) Family	OEP16
1.B.31	The Campylobacter jejuni Major Outer Membrane Porin (MomP) Family	MomP
1.B.32	The Fusobacterial Outer Membrane Porin (FomP) Family	FomP
1.B.33	The Outer Membrane Protein Insertion Porin (Bam Complex) (OmpIP) Family	OmpIP
1.B.34	The Corynebacterial Porin A (PorA) Family	PorA
1.B.35	The Oligogalacturonate-specific Porin (KdgM) Family	KdgM
1.B.36	The Borrelia Porin p13 (BP-p13) Family	BP-p13
1.B.37	The Leptospira Porin OmpL1 (LP-OmpL1) Family	LP-OmpL1
1.B.38	The Treponema Porin Major Surface Protein (TP-MSP) Family	TP-MSP
1.B.39	The Bacterial Porin, OmpW (OmpW) Family	OmpW
1.B.4	The Brucella-Rhizobium Porin (BRP) Family	BRP
1.B.40	The Autotransporter-2 (AT-2) Family	AT-2
1.B.41	The Corynebacterial Porin B (PorB) Family	PorB
1.B.42	The Outer Membrane Lipopolysaccharide Export Porin (LPS-EP) Family	LPS-EP
1.B.43	The Coxiella Porin P1 (CPP1) Family
1.B.44	The Probable Protein Translocating Porphyromonas gingivalis Porin (PorT) Family
1.B.45	The Treponema Porin (T-por) Family
1.B.46	The Outer Membrane LolAB Lipoprotein Insertion Apparatus (LolAB) Family	LolAB
1.B.47	The Plastid Outer Envelope Porin of 37 kDa (OEP37) Family
1.B.48	The Curli Fiber Subunit, CsgA, Porin, CsgG (GsgG) Family
1.B.49	The Anaplasma P44 (A-P44) Porin Family
1.B.5	The Pseudomonas OprP Porin (POP) Family	POP
1.B.50	The Acid-fast Bacterial, Outer Membrane Porin (AFB-OMP) Family	AFB-OMP
1.B.51	The Oms66 Porin (Oms66P) Family
1.B.52	The Oms28 Porin (Oms28P) Family
1.B.53	The Filamentous Phage gp3 Channel-Forming Protein (FP-gp3) Family
1.B.54	The Intimin/Invasin (Int/Inv) or Autotransporter-3 (AT-3) Family
1.B.55	The Poly Acetyl Glucosamine Porin (PgaA) Family
1.B.56	The Spirochete Outer Membrane Porin (S-OMP) Family	S-OMP
1.B.57	The Legionella Major-Outer Membrane Protein (LM-OMP) Family	LM-OMP
1.B.58	Nocardial Hetero-oligomeric Cell Wall Channel (NfpA/B) Family
1.B.59	The Outer Membrane Porin, PorH (PorH) Family	PorH
1.B.6	The OmpA-OmpF Porin (OOP) Family	OOP
1.B.60	The Omp50 Porin (Omp50 Porin) Family	Omp 50 Porin
1.B.61	The Delta-Proteobacterial Porin (Delta-Porin) Family	Delta-Porin
1.B.62	The Putative Bacterial Porin (PBP) Family	(PBP)
1.B.7	The Rhodobacter PorCa Porin (RPP) Family	RPP
1.B.8	The Mitochondrial and Plastid Porin (MPP) Family	MPP
1.B.9	The FadL Outer Membrane Protein (FadL) Family	FadL
1.C.1	The Channel-forming Colicin (Colicin) Family	Colicin
1.C.10	The Pore-forming Haemolysin E (HlyE) Family	HlyE
1.C.100	The Thermostable Direct Hemolysin (TDH) Family	TDH
1.C.101	The HIV-1 TAT Peptide Translocator (HIV-TAT1) Family	HIV-TAT1
1.C.102	The Cerein (Cerein) Family	Cerein
1.C.103	The Pore-forming Toxin, TisB (TisB) Family	TisB
1.C.104	The Heterokaryon Incompatibility Prion/Amyloid Protein (HET-s) Family	HET-s
1.C.105	The Bacillus thuringiensis Vegetative Insecticidal Protein-3 (Vip3) Family	Vip3
1.C.106	The Bacillus thuringiensis Vegetative Insecticidal Protein-2 (Vip2) Family	Vip2
1.C.107	Import Subunit A of the Insecticidal Toxin Complex (ITC-A) Family	ITC-A
1.C.108	The Pore-forming Dermcidin (Dermcidin) Family	Dermcidin
1.C.11	The Pore-forming RTX Toxin (RTX-toxin) Family	RTX-toxin
1.C.12	Thiol-activated Cholesterol-dependent Cytolysin (CDC) Family	TAC
1.C.13	The Channel-forming Leukocidin Cytotoxin (Ctx) Family	Ctx
1.C.14	The Cytohemolysin (CHL) Family	CHL
1.C.15	The Whipworm Stichosome Porin (WSP) Family	WSP
1.C.16	The Magainin (Magainin) Family	Magainin
1.C.17	The Cecropin (Cecropin) Family	Cecropin
1.C.18	The Melittin (Melittin) Family	Melittin
1.C.19	The Defensin (Defensin) Family	Defensin
1.C.2	The Channel-forming δ-Endotoxin Insecticidal Crystal Protein (ICP) Family	ICP
1.C.20	The Nisin (Nisin) Family	Nisin
1.C.21	The Lacticin 481 (Lacticin 481) Family	Lacticin 481
1.C.22	The Lactococcin A (Lactococcin A) Family	Lactococcin A
1.C.23	The Lactocin S (Lactocin S) Family	Lactocin S
1.C.24	The Pediocin (Pediocin) Family	Pediocin
1.C.25	The Lactococcin G (Lactococcin G) Family	Lactococcin G
1.C.26	The Lactacin X (Lactacin X) Family	Lactacin X
1.C.27	The Divergicin A (Divergicin A) Family	Divergicin A
1.C.28	The Bacteriocin AS-48 Cyclic Polypeptide (Bacteriocin AS-48) Family	Bacteriocin AS-48
1.C.29	The Plantaricin EF (Plantaricin EF) Family	Plantaricin EF
1.C.3	The α-Hemolysin Channel-forming Toxin (αHL) Family	aHL
1.C.30	The Plantaricin JK (Plantaricin JK) Family	Plantaricin JK
1.C.31	The Channel-forming Colicin V (Colicin V) Family	Colicin V
1.C.32	The Amphipathic Peptide Mastoparan (Mastoparan) Family	Mastoparan
1.C.33	The Cathelicidin (Cathelicidin) Family	Ca Thelicidin
1.C.34	The Tachyplesin (Tachyplesin) Family	Tachyplesin
1.C.35	The Amoebapore (Amoebapore) Family	Amoebapore
1.C.36	The Bacterial Type III-Target Cell Pore (IIITCP) Family	IIITCP
1.C.37	The Lactococcin 972 (Lactococcin 972) Family	Lactococcin 972
1.C.38	The Pore-forming Equinatoxin (Equinatoxin) Family	Equinatoxin
1.C.39	The Membrane Attack Complex/Perforin (MACPF) Family	CPC9
1.C.4	The Aerolysin Channel-forming Toxin (Aerolysin) Family	Aerolysin
1.C.40	The Bactericidal Permeability Increasing Protein (BPIP) Family	BPIP
1.C.41	The Tripartite Haemolysin BL (HBL) Family	HBL
1.C.42	The Channel-forming Bacillus anthracis Protective Antigen (BAPA) Family	BAPA
1.C.43	The Earthworm Lysenin Toxin (Lysenin) Family	Lysenin
1.C.44	The Plant Thionine (PT) Family	PT
1.C.45	The Plant Defensin (Plant Defensin) Family	PD
1.C.46	The C-type Natriuretic Peptide (CNP) Family	CNP
1.C.47	The Insect/Fungal Defensin (Insect/Fungal Defensin) Family	Insect Defensin
1.C.48	The Prion Peptide Fragment (PrP-F) Family	PrP-F
1.C.49	The Cytotoxic Amylin (Amylin) Family	Amylin
1.C.5	The Channel-forming ε-toxin (ε-toxin) Family	e-toxin
1.C.50	The Amyloid β-Protein Peptide (AβPP) Family	A�PP
1.C.51	The Pilosulin (Pilosulin) Family	Pilosulin
1.C.52	The Dermaseptin (Dermaseptin) Family	Dermaseptin
1.C.53	The Lactocyclicin Q (Lactocyclicin Q) Family
1.C.54	The Shiga Toxin B-Chain (ST-B) Family	ST-B
1.C.55	The Agrobacterial VirE2 Target Host Cell Membrane Anion Channel (VirE2) Family	VirE2
1.C.56	The Pseudomanas syringae HrpZ Target Host Cell Membrane Cation Channel (HrpZ) Family	HrpZ
1.C.57	The Clostridial Cytotoxin (CCT) Family	CCT
1.C.58	The Microcin E492/C24 (Microcin E492) Family
1.C.59	The Clostridium perfringens Enterotoxin (CPE) Family	CPE
1.C.6	The Yeast Killer Toxin K1 (YKT-K1) Family	YKT-K1
1.C.60	The Two-component Enterococcus faecalis Cytolysin (EFC) Family	EFC
1.C.61	The Streptococcus pyogenes Streptolysin S (Streptolysin S) Family	Streptolysin S
1.C.62	The Pseudopleuronectes americanus (flounder) Pleurocidin (Pleurocidin) Family	Pleurocidin
1.C.63	The α-Latrotoxin (Latrotoxin) Family	Latrotoxin
1.C.64	The Fst Toxin (Fst) Family	Fst
1.C.65	The Type III Secretion System Plant Host Cell Membrane Pore-forming HrpF (HrpF) Family	HrpF
1.C.66	The Puroindoline (Puroindoline) Family	Puroindoline
1.C.67	The SphH Hemolysin (SphH) Family	SphH
1.C.68	The Channel-forming Oxyopinin Peptide (Oxyopinin) Family	Oxyopinin
1.C.69	The Clostridium perfringens Beta-2 Toxin (Beta-2) Family	Beta-2
1.C.7	The Diphtheria Toxin (DT) Family	DT
1.C.70	The Streptococcal Pore-forming CAMP Factor (CAMP-F) Family	CAMP-F
1.C.71	The Cytolytic Delta Endotoxin (Cyt1/2) Family	Cyt1/2
1.C.72	The Pertussis Toxin (PTX) Family
1.C.73	The Pseudomonas Exotoxin A (P-ExoA) Family
1.C.74	The Snake Cytotoxin (SCT) Family
1.C.75	The Serratia-type Pore-forming Toxin (S-PFT) Family
1.C.76	The Pore-forming Maculatin Peptide (Maculatin) Family
1.C.77	The Synuclein (Synuclein) Family
1.C.78	The Crystal Protein (Cry) Family
1.C.79	The Channel-forming Histatin Antimicrobial Peptide (Histatin) Family
1.C.8	The Botulinum and Tetanus Toxin (BTT) Family	BTT
1.C.80	The Cytotoxic Major Fimbrial Subunit (MrxA) Family
1.C.81	The Arenicin (Arenicin) Family
1.C.82	The Pore-forming Amphipathic Helical Peptide HP(2-20) (HP2-20) Family
1.C.83	The Gassericin (Gassericin) Family
1.C.84	The Subtilosin (Subtilosin) Family
1.C.85	The Pore-Forming β-Defensin (β-Defensin) Family
1.C.86	The Pore-forming Trialysin (Trialysin) Family
1.C.87	The Phage P22 Cell Envelope-penetrating Needle (P22-CEN) Family
1.C.88	The Chrysophsin (Chrysophsin) Family
1.C.89	The Dynorphin Channel-forming Neuropeptide (Dynorphin) Family
1.C.9	The Vacuolating Cytotoxin (VacA) Family	VacA
1.C.90	The Carnocyclin A (Carnocyclin) Family
1.C.91	The Stefin B Pore-forming Protein (Stefin B) Family
1.C.92	The Pentraxin (Pentraxin) Family
1.C.93	The Lacticin Q (Lacticin Q) Family
1.C.94	The Thuricin S (Thuricin S) Family
1.C.95	The Pore-forming ESAT-6 Protein (ESAT-6) Family
1.C.96	The Haemolytic Lectin, CEL-III (CEL-III) Family
1.C.97	The Pleurotolysin pore-forming (Pleurotolysin) Family
1.C.98	The Cytolethal Distending Toxin (CDT) Family
1.C.99	The Pore-forming Corona Viral Orf8a (Orf8a) Family
1.D.1	The Gramicidin A (Gramicidin A) Channel Family	Gramicidin A
1.D.10	The Ceramide-forming Channel (Ceramide) Family	Ceramide
1.D.11	The Surfactin (Surfactin) Family	Surfactin
1.D.12	The Beauvericin (Beauvericin) Family	Beauvericin
1.D.13	DNA-delivery Amphipathic Peptide Antibiotics (DAPA)	DAPA
1.D.14	The Synthetic Leu/Ser Amphipathic Channel-forming Peptide (l/S-SCP) Family
1.D.15	The Daptomycin (Daptomycin) Family
1.D.16	The Synthetic Amphipathic Pore-forming Heptapeptide (SAPH) Family
1.D.17	Combinatorially-designed, Pore-forming, β-sheet Peptide (CPβ-Peptide) Family
1.D.18	The Pore-forming Guanosine-Bile Acid Conjugate (GBC) Family
1.D.19	Ca²⁺ Channel-forming Drug, Digitoxin (Digitoxin) Family
1.D.2	The Channel-forming Syringomycin (Syringomycin) Family	Syringomycin
1.D.20	The Pore-forming Polyene Macrolide Antibiotic/fungal Agent (PMAA) Family
1.D.21	The Lipid NanoPore (LNP) Family
1.D.22	The Proton-Translocating Carotenoid Pigment, Zeaxanthin (Zeaxanthin) Family
1.D.23	Phenylene Ethynylene Pore-forming Antimicrobial (PEPA) Family
1.D.24	The Marine Sponge Polytheonamide B (pTB) Family
1.D.25	The Arylamine Foldamer (AAF) Family	AAF
1.D.26	The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside (DDDC9G) Family	DDDC9G
1.D.27	The Thiourea isosteres Family
1.D.28	The Lipopeptaibol (Lipopeptaibol) Family
1.D.29	The Macrocyclic Oligocholate (Oligocholate) Family
1.D.3	The Channel-Forming Syringopeptin (Syringopeptin) Family	Syringopeptin
1.D.30	The Artificial Hydrazide-appended pillar[5]arene Channels (HAPA-C) Family
1.D.31	The Amphotericin B (Amphotericin) Family	Amphotericin
1.D.32	The Pore-forming Novicidin (Novicidin) Family	Novicidin
1.D.33	The Channel-forming Polytheonamide B (Polytheonamide B) Family	Polytheonamide B
1.D.34	The Channel-forming Oligoester Bolaamphiphiles	Oligoester Bolaamphiphiles
1.D.35	The Pore-forming cyclic Lipodepsipeptide (Lipodepsipeptide) Family	Lipodepsipeptide
1.D.36	The Oligobornene Ion Channel (Oligobornene) Family	Oligobornene
1.D.4	The Tolaasin Channel-forming (Tolaasin) Family	Tolaasin
1.D.5	The Alamethicin or Peptaibol Antibiotic Channel-forming (Alamethicin) Family	Alamethicin
1.D.6	The Complexed Poly 3-Hydroxybutyrate Ca²⁺ Channel (cPHB-CC) Family	cPHB-CC
1.D.7	The Beticolin (Beticolin) Family	Beticolin
1.D.8	The Saponin (Saponin) Family	Saponin
1.D.9	The Polyglutamine Ion Channel (PG-IC) Family	PG-IC
1.E.1	The P21 Holin S (P21 Holin) Family	P21 Holin
1.E.10	The Bacillus subtilis φ29 Holin (φ29 Holin) Family	f29 Holin
1.E.11	The φ11 Holin (φ11 Holin) Family	f11 Holin
1.E.12	The φAdh Holin (φAdh Holin) Family	fAdh Holin
1.E.13	The Firmicute phage φU53 Holin (φU53 Holin) Family	fU53 Holin
1.E.14	The LrgA Holin (LrgA Holin) Family	LrgA Holin
1.E.15	The ArpQ Holin (ArpQ Holin) Family	ArpQ Holin
1.E.16	The Cph1 Holin (Cph1 Holin) Family	Cph1 Holin
1.E.17	The BlyA Holin (BlyA Holin) Family	BlyA Holin
1.E.18	The Lactococcus lactis Phage r1t Holin (r1t Holin) Family	r1t Holin
1.E.19	The Clostridium difficile TcdE Holin (TcdE Holin) Family	TcdE Holin
1.E.2	The λ Holin S (λ Holin) Family	λ Holin
1.E.20	The Pseudomonas aeruginosa Hol Holin (Hol Holin) Family	Hol Holin
1.E.21	The Listeria Phage A118 Holin (Hol118) Family	Hol118
1.E.22	The Neisserial Phage-associated Holin (NP-Holin) Family	NP-Holin
1.E.23	The Bacillus Spore Morphogenesis and Germination Holin (BSH) Family
1.E.24	The Bacterophase Dp-1 Holin (Dp-1 Holin) Family
1.E.25	The Pseudomonas phage F116 Holin (F116 Holin) Family	F116 Holin
1.E.26	The Holin LLH (Holin LLH) Family	Holin LLH
1.E.27	The BlhA Holin (BlhA Holin) Family	BhlA Holin
1.E.28	The Streptomyces aureofaciens Phage Mu1/6 Holin (Mu1/6 Holin) Family	Mu1/6 Holin
1.E.29	The Holin Hol44 (Hol44) Family	Hol44
1.E.3	The P2 Holin TM (P2 Holin) Family	P2 Holin
1.E.30	The Vibrio Holin (Vibrio Holin) Family	Vibrio Holin
1.E.31	The SPP1 Holin (SPP1 Holin) Family	SPP1 Holin
1.E.32	Actinobacterial 1 TMS Holin (A-1 Holin) Family	A-1 Holin
1.E.33	The 2 or 3 TMS Putative Holin (2/3 Holin) Family	2/3 Holin
1.E.34	The Putative Actinobacterial Holin-X (Hol-X) Family	PAH-X
1.E.35	The Mycobacterial 1 TMS Phage Holin (M1 Hol) Family	M1 Hol
1.E.36	The Mycobacterial 2 TMS Phage Holin (M2 Hol) Family	M2 Hol
1.E.37	The Phage T1 Holin (T1 Holin) Family	T1 Holin
1.E.38	The Staphylococcus phage P68 Putative Holin (P68 Hol) Family	P68 Hol
1.E.39	Mycobacterial Phage PBI1 Gp36 Holin (Gp36 Hol) Family	Gp36 Hol
1.E.4	The LydA Holin (LydA Holin) Family	LydA Holin
1.E.40	The Mycobacterial 4 TMS Phage Holin (MP4 Holin) Family	MP4 Holin
1.E.41	The Deinococcus/Thermus Holin (D/T-Hol) Family	(D/T-Hol
1.E.42	The Putative Holin-like Toxin (Hol-Tox) Family	Hol-Tox
1.E.43	Putative Transglycosylase-associated Holin (T-A Hol) Family	T-A Hol
1.E.44	The Putative Lactococcus lactis Holin (LLHol) Family	LLHol
1.E.45	The Xanthomonas Phage Holin (XanPHol) Family	XanPHol
1.E.46	The Prophage Hp1 Holin (Hp1Hol) Family	Hp1Hol
1.E.47	The Caulobacter Phage Holin (CauHol) Family	CauHol
1.E.48	The Enterobacterial Holin (EBHol) Family	EBHol
1.E.49	The Putative Treponema 4 TMS Holin (Tre4Hol) Family	Tre4Hol
1.E.5	The PRD1 Phage P35 Holin (P35 Holin) Family	P35 Holin
1.E.50	The Beta-Proteobacterial Holin (BP-Hol) Family	BP-Hol
1.E.51	The Putative Listeria Phage Holin (LP-Hol) Family	LP-Hol
1.E.52	The Flp/Fap Pilin Putative Holin (FFPP-Hol) Family	FFPP-Hol
1.E.53	The Toxic Hok/Gef Protein (Hok/Gef) Family	Hok/Gef
1.E.6	The T7 Holin (T7 Holin) Family	T7 Holin
1.E.7	The HP1 Holin (HP1 Holin) Family	HP1 Holin
1.E.8	The T4 Holin (T4 Holin) Family	T4 Holin
1.E.9	The T4 Immunity (T4 Imm) Family	T4 Imm
1.F.1	The Synaptosomal Vesicle Fusion Pore (SVF-Pore) Family
1.G.1	The Viral Pore-forming Membrane Fusion Protein-1 (VMFP1) Family	VMFP1
1.G.10	The Herpes Simplex Virus Membrane Fusion Complex (HSV-MFC) Family
1.G.11	Poxvirus Cell Entry Protein Complex (PEP-C) Family	PEP-C
1.G.12	The Avian Leukosis Virus gp95 Fusion Protein (ALV-gp95) Family	ALV-gp95
1.G.2	The Viral Pore-forming Membrane Fusion Protein-2 (VMFP2) Family	VMFP2
1.G.3	The Viral Pore-forming Membrane Fusion Protein-3 (VMFP3) Family	VMFP3
1.G.4	The Viral Pore-forming Membrane Fusion Protein-4 (VMFP4) Family	VMFP4
1.G.5	The Viral Pore-forming Membrane Fusion Protein-5 (VMFP5) Family	VMFP5
1.G.6	The Hepadnaviral S Fusion Protein (HBV-S Protein) Family	HBV-S Protein
1.G.7	The Reovirus FAST Fusion Protein (R-FAST) Famly
1.G.8	The Arenavirus Fusion Protein (AV-FP) Family	AV-FP
1.G.9	The Syncytin (Syncytin) Family
1.H.1	The Claudin Tight Junction (Claudin) Family
1.H.2	The Invertebrate PMP22-Claudin (Claudin2) Family	Claudin2
1.I.1	The Nuclear Pore Complex (NPC) Family	NPC
1.I.2	The Plant Plasmodesmata (PPD) Family	PPD
1.J.1	The Archaeal Virus-Associated Pyramid (A-VAP) Family	A-VAP
1.K.1	The Gp27/5 T4-baseplate (T4-BP) Family	T4-BP
2.A.1	The Major Facilitator Superfamily (MFS)	MFS
2.A.10	The 2-Keto-3-Deoxygluconate Transporter (KDGT) Family	KDGT
2.A.100	The Ferroportin (Fpn) Family	Fpn
2.A.101	The Malonate Uptake (MatC) Family (Formerly UIT1)	MatC
2.A.102	The Putative 4-Toluene Sulfonate Uptake Permease (TSUP) Family	TSUP
2.A.103	The Bacterial Murein Precursor Exporter (MPE) Family	MPE
2.A.104	The L-Alanine Exporter (AlaE) Family	AlaE
2.A.105	The Mitochondrial Pyruvate Carrier (MPC) Family	MPC
2.A.106	The Ca²⁺:H⁺ Antiporter-2 (CaCA2) Family	CaCA2
2.A.107	The MntP Mn2 exporter (MntP) Family	MntP
2.A.108	The Iron/Lead Transporter (ILT) Family	ILT
2.A.109	The Tellurium Ion Resistance (TerC) Family	TerC
2.A.11	The Citrate-Mg²⁺:H⁺ (CitM) Citrate-Ca²⁺:H⁺ (CitH) Symporter (CitMHS) Family	CitMHS
2.A.110	The heme transporter, heme-responsive gene protein (HRG) Family	HRG
2.A.111	The Na⁺/H⁺ Antiporter-E (NhaE) Family	NhaE
2.A.12	The ATP:ADP Antiporter (AAA) Family	AAA
2.A.13	The C₄-Dicarboxylate Uptake (Dcu) Family	Dcu
2.A.14	The Lactate Permease (LctP) Family	LctP
2.A.15	The Betaine/Carnitine/Choline Transporter (BCCT) Family	BCCT
2.A.16	The Telurite-resistance/Dicarboxylate Transporter (TDT) Family	TDT
2.A.17	The Proton-dependent Oligopeptide Transporter (POT) Family	POT
2.A.18	The Amino Acid/Auxin Permease (AAAP) Family	AAAP
2.A.19	The Ca²⁺:Cation Antiporter (CaCA) Family	CaCA
2.A.2	The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family	GPH
2.A.20	The Inorganic Phosphate Transporter (PiT) Family	PiT
2.A.21	The Solute:Sodium Symporter (SSS) Family	SSS
2.A.22	The Neurotransmitter:Sodium Symporter (NSS) Family	NSS
2.A.23	The Dicarboxylate/Amino Acid:Cation (Na⁺ or H⁺) Symporter (DAACS) Family	DAACS
2.A.24	The 2-Hydroxycarboxylate Transporter (2-HCT) Family	CCS
2.A.25	The Alanine or Glycine:Cation Symporter (AGCS) Family	AGCS
2.A.26	The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family	LIVCS
2.A.27	The Glutamate:Na⁺ Symporter (ESS) Family	ESS
2.A.28	The Bile Acid:Na⁺ Symporter (BASS) Family	BASS
2.A.29	The Mitochondrial Carrier (MC) Family	MC
2.A.3	The Amino Acid-Polyamine-Organocation (APC) Family	APC
2.A.30	The Cation-Chloride Cotransporter (CCC) Family	CCC
2.A.31	The Anion Exchanger (AE) Family	AE
2.A.32	The Silicon Transporter (Sit) Family	Sit
2.A.33	The NhaA Na⁺:H⁺ Antiporter (NhaA) Family	NhaA
2.A.34	The NhaB Na⁺:H⁺ Antiporter (NhaB) Family	NhaB
2.A.35	The NhaC Na⁺:H⁺ Antiporter (NhaC) Family	NhaC
2.A.36	The Monovalent Cation:Proton Antiporter-1 (CPA1) Family	CPA1
2.A.37	The Monovalent Cation:Proton Antiporter-2 (CPA2) Family	CPA2
2.A.38	The K⁺ Transporter (Trk) Family	Trk
2.A.39	The Nucleobase:Cation Symporter-1 (NCS1) Family	NCS1
2.A.4	The Cation Diffusion Facilitator (CDF) Family	CDF
2.A.40	The Nucleobase:Cation Symporter-2 (NCS2) Family	NCS2
2.A.41	The Concentrative Nucleoside Transporter (CNT) Family	CNT
2.A.42	The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family	HAAAP
2.A.43	The Lysosomal Cystine Transporter (LCT) Family	LCT
2.A.45	The Arsenite-Antimonite (ArsB) Efflux Family	ArsB
2.A.46	The Benzoate:H+ Symporter (BenE) Family	BenE
2.A.47	The Divalent Anion:Na⁺ Symporter (DASS) Family	DASS
2.A.48	The Reduced Folate Carrier (RFC) Family	RFC
2.A.49	The Chloride Carrier/Channel (ClC) Family	ClC
2.A.5	The Zinc (Zn²⁺)-Iron (Fe²⁺) Permease (ZIP) Family	ZIP
2.A.50	The Glycerol Uptake (GUP) Family	GUP
2.A.51	The Chromate Ion Transporter (CHR) Family	CHR
2.A.52	The Ni²⁺-Co²⁺ Transporter (NiCoT) Family	NiCoT
2.A.53	The Sulfate Permease (SulP) Family	SulP
2.A.54	The Mitochondrial Tricarboxylate Carrier (MTC) Family	MTC
2.A.55	The Metal Ion (Mn²⁺-iron) Transporter (Nramp) Family	Nramp
2.A.56	The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family	TRAP-T
2.A.57	The Equilibrative Nucleoside Transporter (ENT) Family	ENT
2.A.58	The Phosphate:Na⁺ Symporter (PNaS) Family	PNaS
2.A.59	The Arsenical Resistance-3 (ACR3) Family	ACR3
2.A.6	The Resistance-Nodulation-Cell Division (RND) Superfamily	RND
2.A.60	The Organo Anion Transporter (OAT) Family	OAT
2.A.61	The C₄-dicarboxylate Uptake C (DcuC) Family	DcuC
2.A.62	The NhaD Na⁺:H⁺ Antiporter (NhaD) Family	NhaD
2.A.63	The Monovalent Cation (K⁺ or Na⁺):Proton Antiporter-3 (CPA3) Family	CPA3
2.A.64	The Twin Arginine Targeting (Tat) Family	Tat
2.A.65	The Bilirubin Transporter (BRT) Family	BRT
2.A.66	The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily	MOP
2.A.67	The Oligopeptide Transporter (OPT) Family	OPT
2.A.68	The p-Aminobenzoyl-glutamate Transporter (AbgT) Family	AbgT
2.A.69	The Auxin Efflux Carrier (AEC) Family	AEC
2.A.7	The Drug/Metabolite Transporter (DMT) Superfamily	DMT
2.A.70	The Malonate:Na⁺ Symporter (MSS) Family	MSS
2.A.71	The Folate-Biopterin Transporter (FBT) Family	FBT
2.A.72	The K⁺ Uptake Permease (KUP) Family	KUP
2.A.73	The Short Chain Fatty Acid Uptake (AtoE) Family	ICT
2.A.74	The 4 TMS Multidrug Endosomal Transporter (MET) Family	MET
2.A.75	The L-Lysine Exporter (LysE) Family	LysE
2.A.76	The Resistance to Homoserine/Threonine (RhtB) Family	RhtB
2.A.77	The Cadmium Resistance (CadD) Family	CadD
2.A.78	The Branched Chain Amino Acid Exporter (LIV-E) Family	LIV-E
2.A.79	The Threonine/Serine Exporter (ThrE) Family	ThrE
2.A.8	The Gluconate:H⁺ Symporter (GntP) Family	GntP
2.A.80	The Tricarboxylate Transporter (TTT) Family	TTT
2.A.81	The Aspartate:Alanine Exchanger (AAEx) Family	AAE
2.A.82	The Organic Solute Transporter (OST) Family	OST
2.A.83	The Na⁺-dependent Bicarbonate Transporter (SBT) Family	SBT
2.A.84	The Chloroplast Maltose Exporter (MEX) Family	MEX
2.A.85	The Aromatic Acid Exporter (ArAE) Family
2.A.86	The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22)
2.A.87	The Prokaryotic Riboflavin Transporter (P-RFT) Family
2.A.88	Vitamin Uptake Transporter (VUT or ECF) Family
2.A.89	The Vacuolar Iron Transporter (VIT) Family
2.A.9	The Cytochrome Oxidase Biogenesis (Oxa1) Family	Oxa1
2.A.90	The Vitamin A Receptor/Transporter (STRA6) Family
2.A.91	Mitochondrial tRNA Import Complex (M-RIC) (Formerly 9.C.8)
2.A.92	The Choline Transporter-like (CTL) Family
2.A.93	The Unknown BART Superfamily-1 (UBS1) Family
2.A.94	The Phosphate Permease (Pho1) Family
2.A.95	The 6TMS Neutral Amino Acid Transporter (NAAT) Family
2.A.96	The YaaH (YaaH) Family
2.A.97	The Mitochondrial Inner Membrane K⁺/H⁺ and Ca²⁺/H⁺ Exchanger (LetM1) Family	LetM1
2.A.98	The Putative Sulfate Exporter (PSE) Family	PSE
2.A.99	The 6TMS Ni²⁺ uptake transporter (HupE-UreJ) Family
2.B.1	The Valinomycin Carrier (Valinomycin) Family	Valinomycin
2.B.10	The Synthetic CPP, Transportan (Transportan) Family
2.B.12	The Salinomycin (Salinomycin) Family
2.B.2	The Monensin (Monensin) Family	Monensin
2.B.3	The Nigericin (Nigericin) Family	Nigericin
2.B.4	The Macrotetrolide Antibiotic (MA) Family	MA
2.B.5	The Macrocyclic Polyether (MP) Family	MP
2.B.6	The Ionomycin (Ionomycin) Family	Ionomycin
2.B.7	The Transmembrane α-helical Peptide Phospholipid Translocation (TMP-PLT) Family	TMP-PLT
2.B.8	The Bafilomycin A1 (Bafilomycin) Family
2.B.9	The Cell Penetrating Peptide (CPP) Family	CPP
2.C.1	The TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) Family of Auxiliary Proteins for Energization of Outer Membrane Receptor (OMR)-mediated Active Transport	OMR
3.A.1	The ATP-binding Cassette (ABC) Superfamily	ABC
3.A.10	The H⁺, Na⁺ or H⁺, Na⁺-translocating Pyrophosphatase (M⁺-PPase) Family	H⁺-PPase
3.A.11	The Bacterial Competence-related DNA Transformation Transporter (DNA-T) Family	DNA-T
3.A.12	The Septal DNA Translocator (S-DNA-T) Family	S-DNA-T
3.A.13	The Filamentous Phage Exporter (FPhE) Family	FPhE
3.A.14	The Fimbrilin/Protein Exporter (FPE) Family	FPE
3.A.144	The Functionally Uncharacterized ABC2-1 (U-ABC2-1) Family	U-ABC2-1
3.A.15	The Outer Membrane Protein Secreting Main Terminal Branch (MTB) Family	MTB
3.A.16	The Endoplasmic Reticular Retrotranslocon (ER-RT) Family	ER-RT
3.A.17	The Phage T7 Injectisome (T7 Injectisome) Family
3.A.18	The Nuclear mRNA Exporter (mRNA-E) Family
3.A.19	The TMS Recognition/Insertion Complex (TRC) Family
3.A.2	The H⁺- or Na⁺-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily	F-ATPase
3.A.20	The Peroxisomal Protein Importer (PPI) Family	PPI
3.A.21	The C-terminal Tail-Anchored Membrane Protein Biogenesis/ Insertion Complex (TAMP-B) Family	TAMP-B
3.A.22	The Transcription-coupled TREX/TAP Nuclear mRNA Export Complex (TREX) Family	TREX
3.A.23	The Type VI Symbiosis/Virulence Secretory Pathway (VISP) Family	VISP
3.A.24	Type VII or ESX Protein Secretion System (T7SS) Family	T7SS
3.A.25	The Symbiont-specific ERAD-like Machinery (SELMA) Family	SELMA
3.A.3	The P-type ATPase (P-ATPase) Superfamily	P-ATPase
3.A.4	The Arsenite-Antimonite (ArsAB) Efflux Family	ArsAB
3.A.5	The General Secretory Pathway (Sec) Family	Sec
3.A.6	The Type III (Virulence-related) Secretory Pathway (IIISP) Family	IIISP
3.A.7	The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
3.A.8	The Mitochondrial Protein Translocase (MPT) Family	MPT
3.A.9	The Chloroplast Envelope Protein Translocase (CEPT or Tic-Toc) Family	CEPT or Tic-Toc
3.B.1	The Na⁺-transporting Carboxylic Acid Decarboxylase (NaT-DC) Family	NaT-DC
3.C.1	The Na⁺ Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase (NaT-MMM) Family	NaT-MMM
3.D.1	The H⁺ or Na⁺-translocating NADH Dehydrogenase (NDH) Family	NDH
3.D.10	The Prokaryotic Succinate Dehydrogenase (SDH) Family	SDH
3.D.2	The Proton-translocating Transhydrogenase (PTH) Family	PTH
3.D.3	The Proton-translocating Quinol:Cytochrome c Reductase (QCR) Superfamily	QCR
3.D.4	The Proton-translocating Cytochrome Oxidase (COX) Superfamily	COX
3.D.5	The Na⁺-translocating NADH:Quinone Dehydrogenase (Na-NDH) Family	Na-NDH
3.D.6	The Putative Ion (H⁺ or Na⁺)-translocating NADH:Ferredoxin Oxidoreductase (NFO) Family	NFO
3.D.7	The H₂:Heterodisulfide Oxidoreductase (HHO) Family	HHO
3.D.8	The Na⁺- or H⁺-Pumping Formyl Methanofuran Dehydrogenase (FMF-DH) Family	FMF-DH
3.D.9	The H⁺-translocating F₄₂₀H₂ Dehydrogenase (F₄₂₀H₂DH) Family	F420H2DH
3.E.1	The Ion-translocating Microbial Rhodopsin (MR) Family	MR
3.E.2	The Photosynthetic Reaction Center (PRC) Family	PRC
4.A.1	The PTS Glucose-Glucoside (Glc) Family	Glc
4.A.2	The PTS Fructose-Mannitol (Fru) Family	Fru
4.A.3	The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside (Lac) Family	Lac
4.A.4	The PTS Glucitol (Gut) Family	Gut
4.A.5	The PTS Galactitol (Gat) Family	Gat
4.A.6	The PTS Mannose-Fructose-Sorbose (Man) Family	Man
4.A.7	The PTS L-Ascorbate (L-Asc) Family	L-Asc
4.B.1	The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family
4.C.1	The Proposed Fatty Acid Transporter (FAT) Family
4.C.2	The Carnitine O-Acyl Transferase (CrAT) Family
4.C.3	The Acyl-CoA Thioesterase (AcoT) Family
4.D.1	The Putative Vectorial Glycosyl Polymerization (VGP) Family	VGP
4.D.2	The COG0392; UPF0104 Putative Transporter (COG0392) Family	COG0392
5.A.1	The Disulfide Bond Oxidoreductase D (DsbD) Family	DsbD
5.A.2	The Disulfide Bond Oxidoreductase B (DsbB) Family	DsbB
5.A.3	The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family	PMO
5.B.1	The Phagocyte (gp91^phox) NADPH Oxidase Family	gp91phox
5.B.2	The Eukaryotic Cytochrome b₅₆₁ (Cytb₅₆₁) Family	Cytb561
5.B.3	The Geobacter Nanowire Electron Transfer (G-NET) Family
5.B.4	The Plant Photosystem I Supercomplex (PSI) Family
5.B.5	The Extracellular Metal Oxido-Reductase (EMOR) Family
8.A.1	The Membrane Fusion Protein (MFP) Family	MFP
8.A.10	The Slow Voltage-gated K⁺ Channel Accessory Protein (MinK) Family	MinK
8.A.11	The Immunophilin-like Prolyl:peptidyl Isomerase Regulator (I-PPI) Family	PLB
8.A.12	ABC Bacteriocin Exporter Accessory Protein (BEA) Family	BEA
8.A.13	The Tetratricopeptide Repeat (Tpr1) Family	Tpr1
8.A.14	The Ca²⁺-activated K⁺ Channel Auxiliary Subunit Slowpoke-β (Sloβ) Family	Slo�
8.A.15	The K⁺ Channel Accessory Protein (KChAP) Family	KChAP
8.A.16	The Ca⁺ Channel Auxiliary Subunit γ1-γ8 (CCAγ) Family	CCA?
8.A.17	The Na⁺ Channel Auxiliary Subunit β1-β4 (SCA-β) Family	SCA-�1
8.A.18	The Ca²⁺ Channel Auxiliary Subunit α2δ Types 1-4 (CCA-α2δ) Family	SCA-�2
8.A.19	The Sodium Channel Auxiliary Subunit TipE (SCAT) Family	SCAT
8.A.2	The Secretin Auxiliary Lipoprotein (SAL) Family	SAL
8.A.20	The Plant/Algal/Chlorella Nitrate Transporter Accessory Protein
8.A.21	The Stomatin/Podocin/Band 7/Nephrosis.2/SPFH (Stomatin) Family
8.A.22	The Ca²⁺ Channel Auxiliary Subunit β Types 1-4 (CCA-β) Family
8.A.23	The Basigin (Basigin) Family	Basigin
8.A.24	The Ezrin/Radixin/Moesin-binding Phosphoprotein 50 (EBP50) Family
8.A.25	The Ezrin/Radixin/Moesin (Ezrin) Family
8.A.26	The Caveolin (Caveolin) Family
8.A.27	The Phospholipid Importer β-subunit (PLI-β) Family
8.A.28	The Ankyrin (Ankyrin) Family
8.A.29	The Homer1 (Homer1) Family of Excitation-Contraction Coupling Proteins
8.A.3	The Cytoplasmic Membrane-Periplasmic Auxiliary-1 (MPA1) Protein with Cytoplasmic (C) Domain (MPA1-C or MPA1+C) Family	MPA1-C or MPA1+C
8.A.30	The Nedd4-Family Interacting Protein-2 (Nedd4) Family	Nedd4
8.A.31	The Ly-6 Neurotoxin-like Protein1 Precursor (Lynx1) Family
8.A.32	The β-Amyloid Cleaving Enzyme (BACE1) Family
8.A.33	The Fatty Acid Binding Protein (FABP) Family
8.A.34	The Endophilin (Endophilin) Family
8.A.35	The Mycobacterial Membrane Protein Small (MmpS) Family	MmpS
8.A.36	The Trp-3 (SPE-41) Interaction Protein (SPE-38) Family
8.A.37	The Hepcidin (Hepcidin) Family	Hepcidin
8.A.38	The Animal Macoilin Regulator of ion Channels (Macoilin) Family	Macoilin
8.A.39	The Homeobox; Penetratin (Penetratin) Family
8.A.4	The Cytoplasmic Membrane-Periplasmic Auxiliary-2 (MPA2) Family	MPA2
8.A.40	The Tetraspanin (Tetraspanin) Family	Tetraspanin
8.A.5	The Voltage-gated K⁺ Channel β-subunit (Kvβ) Family	KTN
8.A.6	The Auxiliary Nutrient Transporter (ANT) Family	ANT
8.A.7	The Phosphotransferase System Enzyme I (EI) Family	EI
8.A.8	The Phosphotransferase System HPr (HPr) Family	HPr
8.A.9	The rBAT Transport Accessory Protein (rBAT) Family	rBAT
8.B.1	The Long (4C-C) Scorpion Toxin (L-ST) Superfamily
8.B.10	The Psalmotoxin-1 (PcTx1) Family
8.B.11	The Sea Anemone Peptide Toxin (APETx) Family
8.B.12	The Spider Toxin (STx2) Family
8.B.13	The Sea Anemone Peptide Toxin Class 2 (Kalicludine) Family
8.B.14	The Sea Anemone Peptide Toxin, Class 1 (BgK) Family
8.B.15	The Sea Anenome Peptide Toxin Class 4 (SHTX) Family
8.B.16	The Maurocalcine Family
8.B.17	The Sea Anemone Peptide Toxin Class III (ShI) Family
8.B.18	The Glucose PTS Inhibitor Dysgalacticin (Dysgalacticin) Family
8.B.2	The Short Scorpion Toxin (SST) Superfamily
8.B.3	The Huwentoxin-1 (Huwentoxin-1) Family
8.B.4	The Conotoxin T (Conotoxin) Family
8.B.5	The Na⁺/K⁺/Ca²⁺ Channel Targeting Tarantula Huwentoxin (THT) Family
8.B.6	The Ca²⁺ Channel-targeting Spider Toxin (CST) Family
8.B.7	The Cl^- Channel Peptide Inhibitor (GaTx1) Family
8.B.8	The α-KTx15 scorpion toxin (α-KTx15) Family
8.B.9	The Triflin Toxin (Triflin or CRISP) Family
8.C.1	The Picrotoxin (Picrotoxin) Family
8.C.2	The Talatisamine (Talatisamine) Family
8.C.3	The Bilastine (Bilastine) Family
9.A.1	The Non ABC Multidrug Exporter (N-MDE) Family	PLI
9.A.11	The Dipicolinic Acid Transporter (DPA-T) Family	Ctr1
9.A.12	The Peptidoglycolipid Addressing Protein (GAP) Family	Ctr2
9.A.13	The Colicin J Lysis (Cjl) Family	Cjl
9.A.14	The G-protein-coupled receptor (GPCR) Family	GPCR
9.A.15	The Autophagy-related Phagophore-formation Transporter (APT) Family	APT
9.A.16	The Lysosomal Protein Import (LPI) Family	LPI
9.A.17	The Integral Membrane Peroxisomal Protein Importer-2 (PPI2) Family	PbrT
9.A.18	The Peptide Uptake Permease (PUP) Family	PUP
9.A.19	The Lipid Intermediate Transporter (Arv1) Family	Arv1
9.A.2	The Endomembrane protein-70 (EMP70) Family	EMP70
9.A.20	The Low Affinity Cation Transporter (LACatT) Family	LACatT
9.A.21	The ComC DNA Uptake Competence (ComC) Family	ComC
9.A.22	The Putative Bacillus Transporter or Unknown Function (BTUF) Family	NhaE
9.A.23	The Niacin/Nicotinamide Transporter (NNT) Family
9.A.24	The Mitochondrial Outer Membrane Insertion Pathway (MOM-IP) Family	MOM-IP
9.A.25	The Por Protein Secretin System (PorSS) Family	PorSS
9.A.26	The Lipid-translocating Exporter (LTE) Family
9.A.27	The Non-Classical Protein Exporter (NCPE) Family
9.A.28	The Ethanolamine Facilitator (EAF) Family
9.A.29	The Lantibiotic Immunity Protein (LIP) Family	LIP
9.A.3	The Sorting Nexin27 (SNX27)-Retromer Assembly Apparatus for Recycling Integral Membrane Proteins (SNX27-RetromerAA) Family	SNX27-RetromerAA
9.A.30	The Putative Tmie Gentamiein Uptake Mechanosensitive Channel (Tmie) Family	Tmie
9.A.31	The Putative SdpAB Peptide Antibiotic-like Killing Factor Exporter (SdpAB) Family
9.A.32	The SdpC (Peptide-Antibiotic Killer Factor) Immunity Protein, SdpI (SdpI) Family
9.A.33	The Pyocin R2 Phage P2 Tail Fiber Protein (Pyocin R2) Family
9.A.35	The Peptide Translocating Syndecan (Syndecan) Family
9.A.36	The Ca²⁺-dependent Phospholipid Scramblase (Scramblase) Family
9.A.37	The Nuclear Import Tax Protein (Tax) Family
9.A.38	The Bacteriocin Immunity Protein (BIP) Family
9.A.39	The Gram-positive Bacterial Hemoglobin Receptor (Isd) Family
9.A.4	The YggT or Fanciful K⁺ Uptake-B (FkuB; YggT) Family	PnuC
9.A.40	The HlyC/CorC (HCC) Family
9.A.41	The Capsular Polysaccharide Exporter (CPS-E) Family
9.A.42	The Mycobacterial PPE41 Protein Secretion System (MPSS) Family
9.A.43	The Cadmium tolerance Efflux Pump (CTEP) Family
9.A.45	The Magnesium Transporter1 (MagT1) Family
9.A.46	The Clarin (CLRN) Family	CLRN
9.A.47	The Tight Adherence (Pilus) Biogenesis Apparatus (TABA) Family
9.A.48	The Unconventional Protein Secretion (UPS) System
9.A.5	The Putative Arginine Transporter (ArgW) Family
9.A.50	The Nuclear t-RNA exporter (t-Exporter) Family
9.A.51	The Francisella Siderophore Transporter (FST) Family
9.A.52	The Microcin J25 (Microsin J25) Family
9.A.53	The Eukaryotic Riboflavin Transporter (E-RFT) Family
9.A.54	The Lysosomal Cobalamin (B₁₂) Transporter (L-B₁₂T) Family
9.A.55	The TMEM205 (TMEM205) Family
9.A.56	The Outer Membrane Anion Porin, TsaT (TsaT) Family	TsaT
9.A.57	The RegIII&gamma (RegIII&gamma) Family
9.A.58	The Sweet; PQ-loop; Saliva; MtN3 (Sweet) Family
9.A.59	The Bacteriocin : Enterocin/Pediocin (BEP) Family
9.A.6	The ATP Exporter (ATP-E) Family	ATP-E
9.A.60	The Small Nuclear RNA Exporter (snRNA-E)	snRNA-E
9.A.62	The AAA-ATPase, Bcs1 (Bcs1) Family	Bcs1
9.A.63	The NEAT-domain containing methaemoglobin heme sequestration (N-MHS) Family
9.A.7	Lactoloccin 972 Immunity Protein (LactococcinIP) Family	LactococcinIP
9.A.8	The Ferrous Iron Uptake (FeoB) Family	FeoB
9.A.9	The Low Affinity Fe²⁺ Transporter (FeT) Family	FeT
9.B.1	The Integral Membrane CAAX Protease (CAAX Protease) Family	CAAX Protease
9.B.10	The Putative Tripartite Zn²⁺ Transporter (TZT) Family
9.B.100	The Phage Shock Protein (Psp) Family
9.B.101	The Cytotoxin-associated Gene Product (CagA) Family	CagA
9.B.102	The YedE/YeeE (YedE/YeeE) Family
9.B.103	The Putative Ca²⁺ Uniporter (GC1qR) Family	GC1qR
9.B.104	The Rhomboid Protease Family
9.B.105	The Lead Resistance Fusion Protein (PbrBC) Family	PbrBC
9.B.106	The Pock Size-determining Protein (PSDP) Family	PSDP
9.B.107	The 8TMS Putative Permease (8-PP) Family	(8-PP)
9.B.11	The Dense Granule Protein 6 (GRA6) Family	GRA6
9.B.110	The Putative Polyketide Antibiotic Exporter (PPAE) Family
9.B.111	The 6TMS Lysyl tRNA synthetase (LysS) Family	LysS
9.B.112	The Stress-inducible Transmembrane Protein (TMPIT1) Family	TMPIT1
9.B.113	The Collagen Secretory Protein, Mia3 (Mia3) Family	Mia3
9.B.114	The Vanomycin-sensitivity protein (SanA) Family	SanA
9.B.115	The DUF161 or YitT (YitT) Family	YitT
9.B.116	The Transporter, YvqF (YvqF) Family	YvqF
9.B.117	The LrgB/CidB holin-auxilary protein (LrgB/CidB) Family	LrgB/CidB
9.B.118	The 11 or 12 TMS YhfT (YhfT) Family	YhfT
9.B.119	The Glycan Synthase, Fks1 (Fks1) Family	Fks1
9.B.12	The (Salt or Low Temperature) Stress-induced Hydrophobic Peptide (SHP) Family	SHP
9.B.120	The DUF554 (DUF554) Family	DUF554
9.B.121	The AsmA (AsmA) Family	AsmA
9.B.122	The DUF3592 or PF12158 (DUF3592) Family	DUF3592
9.B.123	The Lysosomal 7-TMS (TM7SF1) Family	TM7SF1
9.B.124	The DUF805 or PF05656 (DUF805) Family	DUF805
9.B.125	The AmpE/CobD (AmpE/CobD) Family	AmpE/CobD
9.B.126	The Putative Lipid Exporter (YhjD) Family	YhjD
9.B.127	The DUF2919 (PF11143) Family	PF11143
9.B.128	The O-antigen Polymerase, WzyE (WzyE) Family	WzyE
9.B.129	The Membrane Protein MLC1 Family	MLC1
9.B.13	The Putative Pore-forming Entericidin (ECN) Family	ECN
9.B.130	The Synaptoporin Family	Synaptoporin
9.B.131	The Post-GPI Attachment Protein (P-GAP2) Family	P-GAP2
9.B.132	9.B.132. The Post-GPI Attachment Protein-3 (P-GAP3) Family	P-GAP3
9.B.133	The Ice Nucleation Protein Secretion System (INP-SS) Family	INP-SS
9.B.134	The Lysosomal Autophagy and Apoptosis-related Protein, TMEM192 (TMEM192) Family	TMEM192
9.B.135	The Membrane Trafficking Yip (Yip) Family	Yip
9.B.136	The 2TMS Membrane Protein, YjcH (YjcH) Family	YjcH
9.B.137	The Putative Cobalt Transporter (CbtC) Family	CbtC
9.B.138	The Putative Mycobacterial Outer Membrane Porin, LprG (LprG; P27) Family	LprG
9.B.139	The Cannabalism Toxin SdpC (SdpC) Family	SdpC
9.B.14	The Putative Heme Handling Protein (HHP) Family	HEP
9.B.140	The 6 TMS (2 TMS x 3) DUF1206 (DUF1206) Family	DUF1206
9.B.141	The YibE/F (YibE/F) Family	YibE/F
9.B.142	The Integral membrane Glycosyltransferase family 39 (GT39) Family	GT39
9.B.143	The 6 TMS DUF1275/Pf06912 (DUF1275) Family	DUF1275
9.B.144	The DUF3367 (DUF3367) Family	DUF3367
9.B.145	The DUF389/PF04087 (DUF389) Family	DUF389
9.B.146	The Putative Undecaprenyl-phosphate N-Acetylglucosaminyl Transferase (MurG) Family	MurG
9.B.147	The 10 TMS Integral Membrane Protein (10-IMP) Family	10-IMP
9.B.148	The 4 TMS Putative DMT (4-DMT) Family	4-DMT
9.B.149	The M50 Peptidase (M50-P) Family	M50-P
9.B.15	The 4 TMS YbhQ (YbhQ) Family
9.B.150	The DUF502 or Cog2928 (DUF502) Family	DUF502
9.B.151	The Uncharacterized 7 TMS Archaeal/Bacterial Protein (7-ABP) Family	7-ABP
9.B.152	9.B.152. The Viral Nuclear Egress Complex (V-NEC) Family	V-NEC
9.B.16	The Putative Ductin Channel (Ductin) Family	Ductin
9.B.17	The VAMP-associated protein (VAP) Family
9.B.18	The SecDF-associated Single Transmembrane Protein, YajC (YajC) Family	SSTP
9.B.19	The Mn²⁺ Homeostasis Protein (MnHP) Family	MnHP
9.B.2	The Integral Membrane CAAX Protease-2 (CAAX Protease2) Family	CAAX Protease2
9.B.20	The Putative Mg²⁺ Transporter-C (MgtC) Family	MgtC
9.B.21	The Frataxin (Frataxin) Family	Frataxin
9.B.22	The Leukotoxin Secretion Morphogenesis Protein C (MorC) Family
9.B.23	The Mistic (Mistic) Family	DVT
9.B.24	The DUF805 or PF05656 (DUF805) Family	DUF805
9.B.25	The Mitochondrial Inner/Outer Membrane Fusion (MMF) Family	MMF
9.B.27	The DedA or YdjX-Z (DedA) Family	YdjX-Z
9.B.28	The Putative Permease Duf318 (Duf318) Family
9.B.3	The Cysteine Protease Binding Protein-8 (CPBP8) Family	CPBP8
9.B.30	The Hly III (Hly III) Family	Hly III
9.B.31	The YqiH (YqiH) Family	YqiH
9.B.32	The DUF3302 or Pfam11742 (YibI) Family	YihI
9.B.33	The Sensor Histidine Kinase (SHK) Family
9.B.34	The Kinase/Phosphatase/Cyclic-GMP Synthase/Cyclic di-GMP Hydrolase (KPSH) Family
9.B.35	The Putative Thyronine-Transporting Transthyretin (Transthyretin) Family	Transthyretin
9.B.36	The Acid Resistance Membrane Protein (HdeD) Family	HdeD
9.B.37	The Huntington-interacting Protein 14 (HIP14) Family
9.B.38	The Myelin Proteolipid Protein (MPLP) Family
9.B.39	The Long Chain Fatty Acid Translocase (lcFAT) Family	lcFAT
9.B.4	The Universal Stress Protein-B (UspB) Family
9.B.40	The DotA/TraY (DotA/TraY) Family	DotA/TraY
9.B.41	The Occludin (Occludin) Family	Occludin
9.B.42	The ExeAB (ExeAB) Secretin Assembly/Export Complex	ExeAB
9.B.43	The YedZ (YedZ) Family	YedZ
9.B.44	The YiaA-YiaB (YiaAB) Family	YiaAB
9.B.45	The Arg/Asp/Asp (RDD) Family
9.B.46	The Staphylococcus aureus Putative Quorum Sensing Peptide Exporter, AgrB (AgrB) Family	AgrB
9.B.47	The γ-Secretase (γ-Secretase) Family	GsgG
9.B.48	The Cyclotide (Cyclotide) Family
9.B.49	The Unknown IT-2 (UIT2) Family	UIT2
9.B.5	The KX Blood-group Antigen (KXA) Family	KXA
9.B.50	The Unknown IT-3 (UIT3) Family	UIT3
9.B.51	The Unknown IT-4 (UIT4) Family	UIT4
9.B.52	The Unknown IT-5 (UIT5) Family	UIT5
9.B.53	6TMS Chlamydial Protein (C6P) Family	C6P
9.B.54	The Unknown IT-7 (UIT7) Family	UIT7
9.B.55	The Unknown IT-8 (UIT8) Family	UIT8
9.B.56	The Unknown IT-9 (UIT9) Family	UIT9
9.B.57	The Unknown IT-10 (UIT10) Family	UIT10
9.B.58	The Unknown IT-11 (UIT11) Family	UIT11
9.B.59	The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family	CstA
9.B.6	The ΦX174 Lysis Protein E (ΦX174-E) Family	ΦX174-E
9.B.60	The Glutamine Dumper 1 (GDU1) Family
9.B.61	The Putative Pore-forming Hydrogenosomal Membrane Protein Hmp35 (Hmp35 ) Family	Hmp35
9.B.62	The Copper Resistance (CopD) Family
9.B.63	Human T-Lymphotropic Virus I P13 protein (HTLV1-P13) Family
9.B.64	The Putative Cholesterol Transporter (Start1) Family
9.B.65	The Putative Transporter (YhgE) Family
9.B.66	The Animal Nonclassical Protein Secretion (NPS) Family
9.B.67	The Putative Inorganic Carbon (HCO₃^-) Transporter/O-antigen Polymerase (ICT/OAP) Family
9.B.68	The Putative Na-independent Organic Solute Carrier Protein (OSCP1) Family
9.B.69	The Putative Cobalt Transporter (CbtAB) Family
9.B.7	The Putative Sulfate Transporter (CysZ) Family
9.B.70	The Multicomponent Putative SpoIIIAE Exporter (SpoIIIA-E) Family
9.B.71	The Camphor Resistance (CrcB) Family
9.B.72	The 4 TMS GlpM (GlpM) Family
9.B.73	Chloroplast Envelope/Cyanobacterial Membrane Protein (CemA) Family	CemA
9.B.74	The Phage Infection Protein (PIP) Family
9.B.75	The Ethanol Utilization/Transport (Eut) Protein Family
9.B.76	The Goadsporin Immunity Protein, GodI (GodI) Family
9.B.77	The Meckel Syndrome Protein (Meckelin) Family
9.B.78	The Minor Capsid Protein, gp7 of Bacillus subtilis Phage SPP1 (gp7) Family
9.B.79	The Putative Metal Transporter (PmtA) Family
9.B.8	The DUF2157 (DUF2157) Family	DUF2157
9.B.80	The Bacillus Phage φ29 (a Podovirus) DNA Ejection System (φ29-E) Family
9.B.81	The MceB Immunity Protein (MceB) Family
9.B.82	Endoplasmic Reticulum Retrieval Protein1 (Putative Heavy Metal Transporter) (Rer1) Family
9.B.83	The Possible Outer Membrane Secretory Protein LeoA (LeoA) Family	LeoA
9.B.84	The Hepatic Selenoprotein-P (SelP or SePP) Family
9.B.85	The Outer Membrane Lipoprotein-A (OmlA) Family	OmlA
9.B.86	The Propionicin (Propionicin) Family
9.B.87	The Selenoprotein P Receptor (SelP-receptor) Family
9.B.88	The Selenoprotein P Hydrogen Selenide Uptake Protein (SelP) Family
9.B.89	The Putative Channel-forming 3TMSs MamF (MamF) Family
9.B.9	The Urate Transporter (UAT) Family	UAT
9.B.90	The Putative Channel Forming 2MTSs MamC (MamC) Family
9.B.91	The Bacteriocin 41 Immunity Protein (Bac41IP) Family
9.B.92	The Folate Receptor (FR) Family
9.B.93	The Spanin (Spanin) Family
9.B.94	The Male Sterility-Associated Mitochondrial Protein (MSMP) Family
9.B.95	The MamG (LG)₄ repeat (MamG) Family
9.B.96	The PE-PGRS Protein Family
9.B.97	The Acyltransferase-3/Putative Acetyl-CoA Transporter (ATAT) Family
9.B.98	The DUF95 (DUF95) Family
9.B.99	The MltA-interacting Protein (MipA) Family	MipA
9.C.1	The Endosomal Oligosaccharide Transporter (EOT)	EOT
9.C.10	The Liver Nicotinic/Nicotinamide Transporter
9.C.11	The Tunneling Nanotube (TNT) Family
9.C.12	The Water Permeable Channels in Frog Auditory Papillar Hair Cells (APHC-C) Family
9.C.13	The Bacterial Endocytosis (BEC) Family
9.C.14	The Intercellular Bacterial Nanotube (IBN) Family	IBN
9.C.15	The Animal Calmodulin-dependent E.R. Secretion Pathway (CSP) Family	CSP
9.C.16	The Proton-pumping H₂:Sulfur Oxidoreductase (H⁺-HSO) Family
9.C.2	Volume-sensitive Anion Channels (VAC)	VAC
9.C.3	The Rhodococcus erythropolis Porin (REP) Family	REP
9.C.4	The Dolichol-linked Oligosaccharide (DO-ERF) Family
9.C.5	The Endoplasmic Reticulum/Golgi ATP/ADP or AMP Antiport Transporters (ATP-T)	ATP-T
9.C.7	The Low-affinity, Calcium-blocked, Nonspecific Cation Channel (NSC1) of Saccharomyces cerevisiae	NSC1
9.C.8	The ABC Lignin Precursor Transporters (ALPT) Family	ALPT
9.C.9	The Acetobacter aceti Acetate Exporter (AAAE)