Search results for:
| Superfamily | Description |
|---|---|
| IT Superfamily | Prakash S, Cooper G, Singhi S, Saier MH. The ion transporter superfamily. Biochim Biophys Acta. 2003 Dec 3;1618(1):79-92. |
| VIC Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81. |
| MFS Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81. Reddy, V.S., M.A. Shlykov, R. Castillo, E.I. Sun, and M.H. Saier, Jr. (2012). The major facilitator superfamily (MFS) revisited. FEBS J. 279: 2022-2035. |
| PTS-AG Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81. |
| APC Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81; Wong, F.H., J.S. Chen, V. Reddy, J.L. Day, M.A. Shlykov, S.T. Wakabayashi, and M.H. Saier, Jr. (2012). The amino acid-polyamine-organocation superfamily. J. Mol. Microbiol. Biotechnol. 22: 105-113. These proteins have two 5 TMS repeats except for NCS2 and SulP which have two 7 TMS repeats. |
| CPA Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81. |
| PTS-GFL Superfamily | Chang A.B., Lin R., Studley W.K., Tran C.V., Saier M.H. Jr. 2004. Phylogeny as a Guide to Structure and Function of Membrane Transport Proteins. Mol Membr Biol. 21(3):171-81.
Nguyen T.X., Yen M.R., Barabote R.D., Saier M.H. Jr. 2006. Topological predictions for integral membrane permeases of the phosphoenolpyruvate:sugar phosphotransferase system. J Mol Microbiol Biotechnol. 11(6):345-60. |
| LysE Superfamily | Vrljic M, Garg J, Bellmann A, Wachi S, Freudl R, Malecki MJ, Sahm H, Kozina VJ, Eggeling L, Saier MH Jr. The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. J Mol Microbiol Biotechnol. 1999;1:327-36. |
| OmpG Superfamily | |
| Cecropin Superfamily | This superfamily may be related to the Melittin superfamily. |
| Aerolysin Superfamily | |
| Opr Superfamily | |
| RTX-toxin Superfamily | |
| - | - |
| YaeT/TpsB Superfamily | |
| BART Superfamily | Mansour, N.M., Sawhney, M., Tamang, D.G., Vogl, C., Saier, M.H. Jr. 2007. The bile/arsenite/riboflavin transporter (BART) superfamily. FEBS Journal 274(3):612-29. |
| Huwentoxin Superfamily | Diao, J., Lin, Y., Tang, J., and Liang, S. (2003). cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena. Toxicon 42: 715-723. |
| Melittin Superfamily | This superfamily may be related to the Cecropin superfamily. |
| Defensin Superfamily | |
| ENaC/P2X Superfamily | 1.A.6 (ENaC) and 1.A.7 (P2X receptor) have similar 3-d structures and are likely to be homologous (Kawate et al, 2009; Gonzales et al, 2009) |
| - | - |
| MACPF Superfamily | |
| Mer Superfamily | |
| Mitochondrial Carrier (MC) Superfamily | 2.A.29 (32 families) |
| General Bacterial Porin (GBP) Superfamily | |
| Bacterial Bacteriocin (BB) Superfamily | *1.C.53 is also shared with the CBB Superfamily |
| Cation Diffusion Facilitator (CDF) Superfamily | |
| TRC/TAMP-B (TRC/TAMP) Superfamily | |
| MspA Superfamily | |
| Circular Bacterial Bacteriocin (CBB) Superfamily | *1.C.53 is also shared with the BB Superfamily (see BB Superfamily list). Maqueda, M., M. Sánchez-Hidalgo, M. Fernández, M. Montalbán-López, E. Valdivia, and M. Martínez-Bueno. (2008). Genetic features of circular bacteriocins produced by Gram-positive bacteria. FEMS Microbiol. Rev. 32: 2-22. |
| Claudin Superfamily | |
| Gap Junction (GJ) Superfamily | |
| Corynebacterial PorA/PorH Superfamily | |
| Viral Envelope Glycoprotein (Env Polyprotein) Superfamily | |
| ABC1, ABC2, ABC3 Superfamilies | as well as the ECF sub-superfamily are all included within the functional ABC superfamily, TC#3.A.1. Their descriptions and constituent families are presented in paragraphs 3 and 4 of the superfamily description under TC#3.A.1. See (Wang, B., M. Dukarevich, E.I. Sun, M.R. Yen, and M.H. Saier, Jr. (2009). Membrane porters of ATP-binding cassette transport systems are polyphyletic. J. Membr. Biol. 231: 1-10.) for more details. |
| Major Intrinsic Protein (MIP) Superfamily | |
| Endomembrane Protein-Translocon (EMPT) Superfamily | Bolte, K., N. Gruenheit, G. Felsner, M.S. Sommer, U.G. Maier, and F. Hempel. (2011). Making new out of old: recycling and modification of an ancient protein translocation system during eukaryotic evolution. Mechanistic comparison and phylogenetic analysis of ERAD, SELMA and the peroxisomal importomer. Bioessays 33: 368-376. |
| T4 Immunity (T4 IMM) Superfamily | |
| Holin Superfamily I | |
| Holin Superfamily II | |
| Holin Superfamily III | |
| Holin Superfamily IV | |
| Holin Superfamily V | |
| Holin Superfamily VI | |
| Holin Superfamily VII | |
| Resistance-Nodulation-Cell Division (RND) Superfamily | 2.A.6 (9 families) |
| Drug/Metabolite Transporter (DMT) Superfamily | 2.A.7 (32 families) |
| Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily | 2.A.66 (12 families) |
| P-type ATPase (P-ATPase) Superfamily | 3.A.3 (32 families) |
