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3.A.1.124.4
The macedocin exporter, McdEFG (Papadelli et al., 2007)

Accession Number:A6MER5
Protein Name:McdF
Length:304
Molecular Weight:34140.00
Species:Streptococcus macedonicus [59310]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Macedocin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Characterization of the gene cluster involved in the biosynthesis of macedocin, the lantibiotic produced by Streptococcus macedonicus.”  Papadelli M.et.al.   17581139

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMMNNIIELK KVKKVYKDIT TVDIEKITVR EGEIYGFLGP NGAGKTTTMK MILSLVDPTS 
61:	GEIFVNKKDI RKDKNYLSQI GSMIEEPSYY PNLTGYENLL VFQKMVGFDE NNIWPTLELV 
121:	GLADEKNRKK LVKAYSLGMK QRLSLAFALV KKPKILLLDE PTNGLDPAGI HEIRELIVEL 
181:	AKEKGLTVFI SSHILPEIEH IADRVGIINH GRLVYEGEIE AIKSNTWIEI GGDFSQSNIV 
241:	HTLVELGTVE ILGASTSHVK LSNIDNNQLA NAVSYLTENG YRIFRVVRES ETLEDIFLSL 
301:	TKEA