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3.A.1.124.4
The macedocin exporter, McdEFG (Papadelli et al., 2007)

Accession Number:A6MER7
Protein Name:McdG
Length:245
Molecular Weight:27982.00
Species:Streptococcus macedonicus [59310]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Macedocin

Cross database links:

References (1)

[1] “Characterization of the gene cluster involved in the biosynthesis of macedocin, the lantibiotic produced by Streptococcus macedonicus.”  Papadelli M.et.al.   17581139

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIDYFKAEWI KNRKVVILAI GLIFLALSSF IGLANFFLDY DVLIEEQMSR VLWGQLTFYN 
61:	GQLLFPAMLA IFSGLIILPE FERKTLEMLR ANQASVKKMV LSKFLLALFL VSVVQAVLFA 
121:	IYLLTLYLSQ IPFQIEDLLL FLRATILSVI GSSSVLMIHS YLMAKTRNFA KSVGVAAIGS 
181:	FSGFIFIMLG GFINQLFPYS QPMIGLRSRA LNDMSFLEFM LFITVNSLYS FIFYWLTVKK 
241:	LENNE