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3.A.1.104.2
The teichoic acid precursor exporter, TarGH. May be specific for the diphospholipid linked disaccharide portion of the teichoic acid precursor (Schirner et al. 2011). TarG is the target of a small antimicrobial inhibitor of S. aureus growth (Swoboda et al. 2009). TarGH is a WTA transporter and has been purified and reconstituted in proteoliposomes (Matano et al. 2017). They showed that a new compound series inhibits TarH-catalyzed ATP hydrolysis even though the binding site maps to TarG, near the opposite side of the membrane. These are the first ABC transporter inhibitors to block ATPase activity by binding to the transmembrane domain.

Accession Number:D1GQ18
Protein Name:Teichoic acid ABC transporter permease protein
Length:270
Molecular Weight:31490.00
Species:Staphylococcus aureus (strain TW20 / 0582) [663951]
Number of TMSs:6
Substrate Teichoic acid

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FASTA formatted sequence
1:	MSAIGTVFKE HVKNFYLIQR LAQFQVKIIN HSNYLGVAWE LINPVMQIMV YWMVFGLGIR 
61:	SNAPIHGVPF VYWLLVGISM WFFINQGILE GTKAITQKFN QVSKMNFPLS IIPTYIVTSR 
121:	FYGHLGLLLL VIIACMFTGI YPSIHIIQLL IYVPFCFFLT ASVTLLTSTL GVLVRDTQML 
181:	MQAILRILFY FSPILWLPKN HGISGLIHEM MKYNPVYFIA ESYRAAILYH EWYFMDHWKL 
241:	MLYNFGIVAI FFAIGAYLHM KYRDQFADFL