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3.A.2.3.2
The A1A0-ATP synthase, Aha ABCDEFHIK or MbbrA1A0 (AhaC has 4 TMSs; each hairpin has a complete Na+-binding motif. Can use Na+ or H+ to synthesize ATP (McMillan et al., 2011).

Accession Number:D3E1Z1
Protein Name:V-type ATP synthase alpha chain
Length:584
Molecular Weight:64222.00
Species:Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / M1) [634498]
Substrate H+, Na+

Cross database links:

Entrez Gene ID: 8770348   
Pfam: PF00006    PF00306    PF02874   
KEGG: mru:mru_0701   

Gene Ontology

GO:0033178 C:proton-transporting two-sector ATPase complex, catalytic domain
GO:0005524 F:ATP binding
GO:0046933 F:hydrogen ion transporting ATP synthase activity, rotational mechanism
GO:0046961 F:proton-transporting ATPase activity, rotational mechanism
GO:0015991 P:ATP hydrolysis coupled proton transport
GO:0042777 P:plasma membrane ATP synthesis coupled proton transport

References (1)

[1] “The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions.”  Leahy S.C.et.al.   20126622

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MINEGNIIKI AGPVIVADGM RGTQMYEVVR VGEAKLIGEI IELEGDTATI QVYEETAGVK 
61:	PGEKVESTGG PLSVELGPGV MGSIFDGIQR PLEVIKGISG DYIARGIDVD SIDKEKKWTF 
121:	EPIAKVGDKV VGGDILGQVQ ETSAVVQKIM VPPMIEGTIK SIASQAEYTV LETIAEIETE 
181:	DGIEEIQMLQ KWPVRKGRPY KEKLDPDIPL ITGQRAQDTF FCLAKGGAAA IPGPFGSGKT 
241:	VTQQQLAKWA DADIVVYIGC GERGNEMTEV LTEFPFLTDP KTGNPIMDRT VLIANTSNMP 
301:	VAAREACVYT GITIAEYFRD QGYDVALMAD STSRWAEAMR EISGRLEEMP GEEGYPAYLA 
361:	SRLAQFYERA GRVITLGQDP KESSVTVVGA VSPPGGDLSE PVTQNTLRIC KVFWALDASL 
421:	ADKRHFPSIN WLQSYSLYVE SITNWWQENA SEEWRANRDQ AMVLLQKESE LEEIVQLVGP 
481:	DALPDSEQVV LETTRMLRED FLQQNAYDDV DTYCSPIKQA GMLETILKFH EAASAAVTRG 
541:	ADVKEIAALT VKEDIARMKY IPEDEFEARV KEIQEKVVTQ CAEV