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3.A.1.14.28
Iron-siderophore (staphylobactin, made by S. aureus) uptake system, SirABCD (A = periplasmic receptor (R); B and C = membrane proteins with 9 or 10 TMSs (M), and D (IsdC) is likely to be the periplasmic auxiliary protein with 2 TMSs, N- and C-terminal (Dale et al. 2004). This last protein is also given the TC# 9.A.39.1.2 as a member of its own family. The ATPase subunit is not known, but it could be the protein with genbank acc# WP_001080807.1.

Accession Number:O87493
Protein Name:Iron ABC transporter permease
Length:332
Molecular Weight:35730.00
Species:Staphylococcus aureus [1280]
Number of TMSs:10
Substrate

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTEKINKKDN YHLIFALIFL AIVSVVSMMI GSSFIPLQRV LMYFINPNDS MDQFTLEVLR 
61:	LPRITLAILA GAALGMSGLM LQNVLKNPIA SPDIIGITGG ASLSAVVFIA FFSHLTIHLL 
121:	PLFAVLGGAV AMMILLVFQT KGQIRPTTLI IIGISMQTLF IALVQGLLIT TKQLSAAKAY 
181:	TWLVGSLYGA TFKDTIILGM VILAVVPLLF LVIPKMKISI LDDPVAIGLG LHVQRMKLIQ 
241:	LITSTILVSM AISLVGNIGF VGLIAPHIAK TIVRGSYAKK LLMSAMIGAI SIVIADLIGR 
301:	TLFLPKEVPA GVFIAAFGAP FFIYLLLTVK KL