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3.A.1.6.3
Sulfate porter

Accession Number:P0A4W2
Protein Name:Sulfate/thiosulfate import ATP-binding protein CysA aka RV2397C aka MT2468 aka MTCY253.24
Length:353
Molecular Weight:37703.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Sulfate

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_336950.1    YP_177879.1   
Entrez Gene ID: 885663    925874   
Pfam: PF00005    PF03459   
KEGG: mtc:MT2468    mtu:Rv2397c   

Gene Ontology

GO:0043190 C:ATP-binding cassette (ABC) transporter complex
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015419 F:sulfate transmembrane-transporting ATPase a...
GO:0008272 P:sulfate transport

References (3)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036
[3] “Functional genomics reveals the sole sulphate transporter of the Mycobacterium tuberculosis complex and its relevance to the acquisition of sulphur in vivo.”  Wooff E.et.al.   11929522

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKMTYAIVVA DATKRYGDFV ALDHVDFVVP TGSLTALLGP SGSGKSTLLR TIAGLDQPDT 
61:	GTITINGRDV TRVPPQRRGI GFVFQHYAAF KHLTVRDNVA FGLKIRKRPK AEIKAKVDNL 
121:	LQVVGLSGFQ SRYPNQLSGG QRQRMALARA LAVDPEVLLL DEPFGALDAK VREELRAWLR 
181:	RLHDEVHVTT VLVTHDQAEA LDVADRIAVL HKGRIEQVGS PTDVYDAPAN AFVMSFLGAV 
241:	STLNGSLVRP HDIRVGRTPN MAVAAADGTA GSTGVLRAVV DRVVVLGFEV RVELTSAATG 
301:	GAFTAQITRG DAEALALREG DTVYVRATRV PPIAGGVSGV DDAGVERVKV TST