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3.A.1.14.2
Iron (Fe3+)-enterobactin porter

Accession Number:P23876
Protein Name:FepD aka B0590
Length:334
Molecular Weight:33871.00
Species:Escherichia coli [83333]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fe3+-enterobactin

Cross database links:

Genevestigator: P23876
EchoBASE: EB0292
EcoGene: EG10296
eggNOG: COG0609
HEGENOM: HBG700016
RefSeq: AP_001237.1    NP_415122.1   
Entrez Gene ID: 945214   
Pfam: PF01032   
BioCyc: EcoCyc:FEPD-MONOMER    ECOL168927:B0590-MONOMER   
KEGG: ecj:JW0582    eco:b0590   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006826 P:iron ion transport

References (5)

[1] “Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.”  Shea C.M.et.al.   1838574
[2] “Organization of genes encoding membrane proteins of the Escherichia coli ferrienterobactin permease.”  Chenault S.S.et.al.   1787794
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGSVAVTRA IAVPGLLLLL IIATALSLLI GAKSLPASVV LEAFSGTCQS ADCTIVLDAR 
61:	LPRTLAGLLA GGALGLAGAL MQTLTRNPLA DPGLLGVNAG ASFAIVLGAA LFGYSSAQEQ 
121:	LAMAFAGALV ASLIVAFTGS QGGGQLSPVR LTLAGVALAA VLEGLTSGIA LLNPDVYDQL 
181:	RFWQAGSLDI RNLHTLKVVL IPVLIAGATA LLLSRALNSL SLGSDTATAL GSRVARTQLI 
241:	GLLAITVLCG SATAIVGPIA FIGLMMPHMA RWLVGADHRW SLPVTLLATP ALLLFADIIG 
301:	RVIVPGELRV SVVSAFIGAP VLIFLVRRKT RGGA