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3.A.1.6.3
Sulfate porter

Accession Number:P71745
Protein Name:CysT aka RV2399C aka MTCY253.22 aka MT2470
Length:283
Molecular Weight:29683.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Sulfate

Cross database links:

HEGENOM: HBG685300
RefSeq: NP_216915.1    NP_336952.1   
Entrez Gene ID: 885301    925871   
Pfam: PF00528   
KEGG: mtc:MT2470    mtu:Rv2399c   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015116 F:sulfate transmembrane transporter activity
GO:0015563 F:uptake transmembrane transporter activity
GO:0008272 P:sulfate transport

References (3)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.”  Raman K.et.al.   19099550
[3] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTESLVGERR APQFRARLSG PAGPPSVRVG MAVVWLSVIV LLPLAAIVWQ AAGGGWRAFW 
61:	LAVSSHAAME SFRVTLTIST AVTVINLVFG LLIAWVLVRD DFAGKRIVDA IIDLPFALPT 
121:	IVASLVMLAL YGNNSPVGLH FQHTATGVGV ALAFVTLPFV VRAVQPVLLE IDRETEEAAA 
181:	SLGANGAKIF TSVVLPSLTP ALLSGAGLAF SRAIGEFGSV VLIGGAVPGK TEVSSQWIRT 
241:	LIENDDRTGA AAISVVLLSI SFIVLLILRV VGARAAKREE MAA