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3.B.1.1.1
Na+-transporting oxalo-acetate decarboxylase. Subunit stoichiometries have been described (Balsera et al., 2011). The crystal structure of the carboxyltransferase at 1.7 A resolution shows a dimer of alpha(8)beta(8) barrels with an active site metal ion, identified spectroscopically as Zn2+ (Granjon et al. 2010).

Accession Number:Q03030
Protein Name:DCOA aka OADA1 aka OADA aka STM0055 aka OADA2 aka STM3352
Length:591
Molecular Weight:63207.00
Species:Salmonella typhimurium [90371]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion outer membrane1 / Single-pass membrane protein2
Substrate Na+

Cross database links:

HEGENOM: HBG717218
RefSeq: NP_459060.1    NP_462262.1   
Entrez Gene ID: 1251573    1254875   
Pfam: PF00364    PF00682    PF02436   
BioCyc: STYP99287:STM0055-MONOMER    STYP99287:STM3352-MONOMER   
KEGG: stm:STM0055    stm:STM3352   

Gene Ontology

GO:0009374 F:biotin binding
GO:0008948 F:oxaloacetate decarboxylase activity
GO:0008152 P:metabolic process
GO:0006814 P:sodium ion transport

References (2)

[1] “Sequence of the sodium ion pump oxaloacetate decarboxylase from Salmonella typhimurium.”  Woehlke G.et.al.   1331067
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTIAITDVVL RDAHQSLFAT RLRLDDMLPI AAALDDVGYG SLECWGGATF DACIRFLGED 
61:	PWLRLRELKK AMPKTPLQML LRGQNLLGYR HYADDVVERF VERAVKNGMD VFRVFDAMND 
121:	PRNMKAALQA VRSHGAHAQG TLSYTTSPAH TLQTWLDLTE QLLETGVDSI AIKDMSGILT 
181:	PMAAYELVSE IKKRFEVRLH LHCHATTGMA EMALLKAIEA GVDGVDTAIS SMSATYGHPA 
241:	TEALVATLAG TEHDTGLDIL KLENIAAYFR EVRKKYHAFE GQLKGYDSRI LVAQVPGGML 
301:	TNLESQLKQQ NAADKLDQVL AEIPRVREDL GFIPLVTPTS QIVGTQAVLN VLTGERYKTI 
361:	AKETAGILKG EYGHTPVPVN AALQARVLEG GAPVTCRPAD LLKPELAELE ADVRRQAQEK 
421:	GITLAGNAID DVLTVALFPQ IGLKFLENRN NPAAFEPLPQ AEAAQPVAKA EKPAASGIYT 
481:	VEVEGKAFVV KVSDGGDISQ LTAAVPAASS APVQAAAPAG AGTPVTAPLA GNIWKVIATE 
541:	GQTVAEGDVL LILEAMKMET EIRAAQAGTV RGIAVKSGDA VSVGDTLMTL A