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3.A.1.127.1
Exporter of AmfS extracellular peptidic morphogen (Chater and Horinouchi, 2003; Ueda et al., 2002)

Accession Number:Q07639
Protein Name:AmfB
Length:639
Molecular Weight:65195.00
Species:Streptomyces griseus [1911]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (2)

[1] “A gene cluster involved in aerial mycelium formation in Streptomyces griseus encodes proteins similar to the response regulators of two-component regulatory systems and membrane translocators.”  Ueda K.et.al.   8458843
[2] “Characterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus.”  Ueda K.et.al.   9748440

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRLHPRPGTE SGTRRLARQH PAALLLGLLL CSTGGALAAL ALPAALGHTV DLLIAGGPVP 
61:	WPGLLLCAAL ILAETAFDAT AAVTGTTTTA RLTASLRTRT AARVLAAEPR RALALPTGDL 
121:	TARLTARTAD AAAAPVTAAG AVSGVLLPLG AIAGLLLIDV WTAAALLLGA PLLVALLRAF 
181:	TRRTADAGAD YQRAQSLIAH RLTEALDGAD TIRAARTGAR EHRRVLEPLT ALAEHGRRTW 
241:	SVYGRAVGRS GLLLPLLMLL VLAVAGLRLG AGAIGVGDLV AASRYASLAV GIGALTGALG 
301:	ALARSRAAAR SLDPLLALPP LPHRGLGPAP DAPGHLELRD VGVEQDGGRL LTGVDLTVPG 
361:	GTSLAVVGRS GSGKSVLAAV AGRLLDPDTG SVLLDGVPMD GMEPDRLRRE VAYAFARPAL 
421:	PGTTVEDTIA YGPWTASPEA VRDAARAARA DGFLALLPYG YATPLADAPL SGGERQRLGL 
481:	ARAFAHPGRL MILDDALSSL DTVTEHHVRR ALDARAGHCT RIVVAHRLSS AARADRVAWL 
541:	EDGRIRATGR HEELWADPDY RAVFRTEATR AEGPAPAGNP APAGNPAPAG NPAPADEAAP 
601:	PENPAPSDDA APAAGSAPTE IAAPASRTTV TPAAGAEAR