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3.A.1.5.10
Oligopeptide porter (transports peptides of 4-35) amino acyl residues; di- and tripeptides are not transported; hydrophobic basic peptides are preferred). OppA determines the specificity of the system (Doeven et al., 2004). A large cavity in OppA binds proline-rich peptides preferentially (Berntsson et al., 2009). Two crystal structures of OppA with different nonapeptides show binding in different registers (Berntsson et al., 2011).

Accession Number:Q07733
Protein Name:OppD
Length:338
Molecular Weight:37383.00
Species:Lactococcus lactis subsp. lactis (Streptococcus lactis) [1360]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Oligopeptides

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_267998.1   
Entrez Gene ID: 1115506   
Pfam: PF00005    PF08352   
BioCyc: LLAC272623:L93148-MONOMER   
KEGG: lla:L93148   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0015197 F:peptide transporter activity
GO:0015833 P:peptide transport
GO:0015031 P:protein transport

References (2)

[1] “Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis.”  Tynkkynen S.et.al.   8244921
[2] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MESENILEAK QVSVAFRIAG KFQKAIYDID LSLRRGEVLA IVGESGSGKS TFATAVMGLH 
61:	NPNQTQITGS ILLDEEEVIG KTGDSMASIR GSKVGMIFQN PLTALNPLMK IGQQIKEMLA 
121:	VHDVYPENQY ESRIFQLLEQ VGIPNPKRVV NQFPHQLSGG MRQRVMIAIA IANDPDLIIA 
181:	DEPTTALDVT IQAQILDLIL EIQKKKNAGV ILITHDLGVV AEVADTVAVM YAGQLVEKAS 
241:	VEELFQNPKH PYTRSLLRSN PSAETVSDDL YVIPGSVPSL SEIEYDKDLF LARVPWMKEE 
301:	AQKVISEKMT EISSNHFVRG QAWKKFEFPD QKLKGGKK