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3.A.1.27.4
The cholesterol uptake porter (Mohn et al., 2008). Takes up cholesterol, 5-α-cholestanol, 5-α-cholestanone, β-sitosterol, etc. (It is not established that all of these proteins comprise the system or that other gene products are not involved.)

Accession Number:Q0S7K3
Protein Name:Putative uncharacterized protein
Length:283
Molecular Weight:29471.00
Species:rhodococcus sp. (strain rha1) [101510]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2 / Cytoplasmic side3
Substrate cholesterol

Cross database links:

eggNOG: COG0767
HEGENOM: HBG564941
RefSeq: YP_704641.1   
Entrez Gene ID: 4222248   
Pfam: PF02405   
BioCyc: RSP101510:RHA1_RO04697-MONOMER   
KEGG: rha:RHA1_ro0469   

References (1)

[1] “The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.”  McLeod M.P.et.al.   17030794

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALAAAGRFP RTRKRFASAS RSIDRLGEQA LFFARAIGWA PRALMHYPKE TLRLIAEISM 
61:	GTGALAVIGG TVVIVGFLTL FTGGTIAVQG YSSLGNIGVE ALTGFFAAFI NVRIAAPVIA 
121:	GIGLAATIGA GSTAQLGAMR VSEEIDALET MAIPSIPYLV STRVMAGMIA IIPLYALAVI 
181:	ASFMASRFAT VVLYDQSSGV YDHYFSTFLI PTDILWSFAQ AIVMAIAIML IHTYYGFNAS 
241:	GGPVGVGVAV GNAVRSSLIA VVTVTLLISL AIYGASGNFN LSG