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3.A.1.23.1
Nickel (Ni2+) porter (Chen and Burne, 2003)

Accession Number:Q79CJ0
Protein Name:Nickel permease UreQ
Length:259
Molecular Weight:29091.00
Species:Streptococcus salivarius [1304]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ni2+

Cross database links:

Pfam: PF02361   

Gene Ontology

GO:0015087 F:cobalt ion transmembrane transporter activity
GO:0009236 P:cobalamin biosynthetic process
GO:0006824 P:cobalt ion transport

References (1)

[1] “Streptococcus salivarius urease: genetic and biochemical characterization and expression in a dental plaque streptococcus.”  Chen Y.-Y.M.et.al.   8550211

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MILPDWMSEE RPVVTKVGRN NFLIRNRHHL EALLQKFETH PLKVASVFHP TAKVLLLFFL 
61:	LVSVGISRNL TVLWIVALFL GAGVAFLPHS VLVRTLKKTV VLLIFPLVLY LPHLLLSGGQ 
121:	SLFLFRLPLI AVAIAYYSET STISEMLAAL KGLHFPDLVL LQLDITIKYI DVLGKQLMDL 
181:	LKGIEARSFG GNHRFRIGSN IWGILYLKAI RYGEELTQAM EARCFVGEYV KSSQSFTWKD 
241:	WLALISLVAV ILGQILLGG