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3.A.1.23.1
Nickel (Ni2+) porter (Chen and Burne, 2003)

Accession Number:Q79CJ1
Protein Name:Nickel permease UreM
Length:325
Molecular Weight:35158.00
Species:Streptococcus salivarius [1304]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ni2+

Cross database links:

Pfam: PF01891   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0009236 P:cobalamin biosynthetic process

References (1)

[1] “Streptococcus salivarius urease: genetic and biochemical characterization and expression in a dental plaque streptococcus.”  Chen Y.-Y.M.et.al.   8550211

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHIPENYLSP MTCAAMGAVM LPIWYKAVKE VKVKVDTDKK TIPMLGIGTS LSFLIMMFNL 
61:	PAPGGTSAHA VGAVLIAILL GPWASCLAVS VALAMQALLF GDGGILAFGA NAFCMAVVMP 
121:	FVGYAVYKLL NKWTKNRIIA SFFGGYIGIV VAALTVAVLL GIQPILFKDS SGNPLYNPYP 
181:	LRVTLPVMGL THLLIGLVEG FFTAGVQEFI ERLNIDNTQE ITTKKLRPLL LFILALIILT 
241:	PLGLLATGTA FAEWDVKELV EKLSHYHVEA QAPKGMLNGF SFNALFPDYS IAGIPEVLGY 
301:	ILSAASAVLI FFILYRLIFG RKVEK