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3.A.1.4.5
The high affinity urea/thiourea/hydroxyurea porter (Beckers et al., 2004)

Accession Number:Q8NRV9
Protein Name:UrtC
Length:359
Molecular Weight:37872.00
Species:Corynebacterium glutamicum [1718]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Thiourea, Hydroxyurea, Urea

Cross database links:

HEGENOM: HBG655109
RefSeq: NP_600160.1    YP_225224.1   
Entrez Gene ID: 1018924    3343399   
Pfam: PF02653   
BioCyc: CGLU196627:CG1064-MONOMER   
KEGG: cgb:cg1064    cgl:NCgl0895   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSTQLKLKKP AKKKTTPKLS VVNAPTLRTA ALGLAALAAV LLCAPLFLST FQLTLMSRLV 
61:	CYAIVAVGIG LAWGRGGMLT LGQGVFFGIG AYIMAMHMLY SDSQIFGTTV PQWWSIFANP 
121:	AVALIAVVAL PGIVAFVLGF SIFKRRIKGA YFAIVNQALA AAVVVLLVGQ QDSLGGSNGL 
181:	SGFRSFMGFA VYDPINRIMF YFTAVGVLLA LVAISYWLMR SRYGELLVAT RDAEERVRFL 
241:	GYDPALIKTA AYVIAAMIAG IAGALFVPIV GIISPAEIGV VPSIVFVIAV AAGGRASLFG 
301:	PVVGALVLGW VESTLAQTFP SMWSYFQGAI LVLVIVLLPG GIASIKLSAL KNKARKATS