TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.4.5
The high affinity urea/thiourea/hydroxyurea porter (Beckers et al., 2004)

Accession Number:Q8NRW0
Protein Name:UrtA
Length:294
Molecular Weight:30933.00
Species:Corynebacterium glutamicum [1718]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Thiourea, Hydroxyurea, Urea

Cross database links:

HEGENOM: HBG728273
RefSeq: NP_600159.1    YP_225223.1   
Entrez Gene ID: 1018923    3343688   
Pfam: PF02653   
BioCyc: CGLU196627:CG1062-MONOMER   
KEGG: cgb:cg1062    cgl:NCgl0894   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDILLNQLVA GLSVGSVLLL VAVGLSLTFG QMGVINMAHG EFIMVGAYTA YVVQLVVGSA 
61:	GLSLLISIPL AFIIGGLFGV LLEQFLLKYL YHRPLDTLLA TFGVGLILQQ LARNIFGAPA 
121:	VDVRAPEFLR GNVEVLGVLV PTARLFILAL AIASVTALAV FLNRTAWGRR IRAVVLNRDL 
181:	AETAGIDTRA TDRMTFFVGS GLAGIAGVAI TLIGATGPTI GQNYIVDAFL VVAAGGIGRV 
241:	KGAVIMAFVL GITQAFVEYT TGASIAKFIV LIAVVAFLQF RPQGLFQTQT RSLV