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3.A.1.134.2
The bacitracin-resistance (putative bacitracin exporter), MbrAB. Participate with BreSR to control its own gene expression (Bernard et al., 2007).

Accession Number:Q8VUH1
Protein Name:MbrB aka SMU.1007
Length:667
Molecular Weight:75824.00
Species:Streptococcus mutans [1309]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Bacitracin

Cross database links:

HEGENOM: HBG698792
RefSeq: NP_721402.1   
Entrez Gene ID: 1028339   
Pfam: PF02687   
BioCyc: SMUT210007:SMU_1007-MONOMER   
KEGG: smu:SMU.1007   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (2)

[1] “Genes involved in bacitracin resistance in Streptococcus mutans.”  Tsuda H.et.al.   12435673
[2] “Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.”  Ajdic D.J.et.al.   12397186

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MFYLKLALNN IKQSFKHFTP FFLVSVTTFI FSTITVLLMT SPSAKSMGAG VYALGLATIV 
61:	LDILAAILCL YSYNFLLKQR NKEFGLYNIL GMNKKHIIWV STLELIVAYL VTIILGTFLS 
121:	AVLSNFFYLI FVNIIQYEDL NFQLTLPAFV INLILFAVIF LFLELVNIIK ISKTSALNLF 
181:	SNQSQGEREP RGNIVLAFIA ILAIGYGYYL SVTSGNVNAI FGITRFFQAI LAVILGTYLF 
241:	YISFTTWYLK RRRKNKSYFY QPEHFVTTSQ MIFRMKQNAV GLANITLLAI MAFVTIFSTV 
301:	ALYTSSENMV KMAYPKNAQI EMKHISNRQQ AEEIFQKQVL APLKRAGYNS KAKFSAYLDI 
361:	SYPVLFTQKQ NLVLDKSIAT NRTFYKNNHA GTMEIITQDD FRSIGNKVPQ LSAGEVAFYS 
421:	YSQNTTVKPF KTLTWFGQTY KNVYHIKSIK NMVISNSATP AGILVVPDDA TMEAMRKPYD 
481:	DASKYDYTYT FLAFANLTNK EKQVLNRMSQ AKHGLLYGDD DIAVLYSTAA NYRTEGLRMT 
541:	GGFLFTGFLL GIAFLLGAAL IIYYKQLSEG TQDKRSYKIL QEVGMSLKQI KKTINSQIIL 
601:	VFFLPLLMAI VHFVFALPIL KKLLFLFGVQ GDKFLYTVSA LTVVGILIIY FIIYKLTSRT 
661:	YYKIIER