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3.A.1.134.2
The bacitracin-resistance (putative bacitracin exporter), MbrAB. Participate with BreSR to control its own gene expression (Bernard et al., 2007).

Accession Number:Q8VUH2
Protein Name:MbrA
Length:250
Molecular Weight:28373.00
Species:Streptococcus mutans [1309]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Bacitracin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Genes involved in bacitracin resistance in Streptococcus mutans.”  Tsuda H.et.al.   12435673

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFLEINHLEK VFRTRFSKEE THALQDVDFK VDKGEFIAIM GESGSGKTTL LNILATLEKP 
61:	TNGAVILNGQ DITKIKENNL AKFRLKNLGF VFQEFNLLDT LSVKDNIFLP LVLARKDYKE 
121:	MEKHLYRLAP KLRIQNLLEK RPFELSGGQK QRVAIARSLI TNPQILLADE PTAALDYRNS 
181:	EDLLNLFEAI NNDDQTILMV THSANAASHA KRVLFIKDGR IFHQLYRGNK SNQEFSKEIS 
241:	LSMAALLGGE