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3.A.1.134.1
The lantibiotic, salivericin A exporter, SalXY

Accession Number:Q9F443
Protein Name:SalY
Length:635
Molecular Weight:71930.00
Species:Streptococcus salivarius [1304]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Salivericin

Cross database links:

Pfam: PF02687   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (3)

[1] “Isolation and characterization of the lantibiotic salivaricin A and its structural gene salA from Streptococcus salivarius 20P3.”  Ross K.F.et.al.   8357242
[2] “Intra- and interspecies signaling between Streptococcus salivarius and Streptococcus pyogenes mediated by SalA and SalA1 lantibiotic peptides.”  Upton M.et.al.   11395456
[3] “Salivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain Streptococcus salivarius K12.”  Hyink O.et.al.   17194838

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MIWSITKSNI KKNFPLYRIY FLATIGLLSI FIAFLNFISD KIIAEKIGDS GQALVIANGS 
61:	LLFLIVFLVV FLIYFNNFFV KKRSQDLGVL AILGFSKREL TKLLTLENLV ILVLSYLVSL 
121:	LLGPTLYFLA VLVITHLLDL TMEVQWFITV KEIIESLGIL VVVFLINFIT NGVIIAKQSL 
181:	IEFVNFSKKA EKKIRIRKVR AIIAITALLL SYVLCLTTVF SSTRKMLLSV GMVPISLLII 
241:	ILVILGSIFT IRYGLTFVIS FLKEKKKRLY RPLSNIIYPK FNYRIATKNK LLTVLGGLLT 
301:	LTVSVTGIMV MLYAYSLNGI ERLTPSAIEY NVESENGQVN VTNILENGQV SLVDINLLRL 
361:	NTNPEVTITE SGQTIPYFDI INYSDYKELM KAQGRKNSIE GSESLPLLIN YFPTEISLGK 
421:	TFNLENAYDV TVKQVSTNNV FSFSTSVTTL VVSDKLYAEL SSRFPEKKMT IRTFNGDSIR 
481:	SSETFYNQFS TVPDVISSYS REHTVKTANI ATYIFITFLS ILFIICTGSI LYFTSLIEIM 
541:	ENKEEYSYLS KLGYSKKMIN RIVGYEIGIL FLIPVLIGII NGSMLLIFYK YLFMDTLVAG 
601:	NIIMLSLLLF LFFFLIIYGT FYLLTLRSVK SIINN