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3.A.1.32.1
The putative cobalamin precursor uptake transporter, CbrTUV (Rodionov et al., 2009) (CbrT is most similar to 2.A.1.15.1; CbrU is most similar to 3.A.1.26.1 (MFS; e-4); CbrV is most similar to 2.A.53.11.1 and 3.A.1.2.2 (score of 0.035)) (CbrT has 6 putative TMSs; CbrV has 8-10 putative TMSs).

Accession Number:Q9KXJ6
Protein Name:Putative ABC transporter ATP-binding protein SCO2324
Length:563
Molecular Weight:59587.00
Species:Streptomyces coelicolor [1902]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Cobalamin

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_626571.1   
Entrez Gene ID: 1097758   
Pfam: PF00005   
BioCyc: SCOE100226:SCO2324-MONOMER   
KEGG: sco:SCO2324   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0006810 P:transport

References (1)

[1] “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).”  Bentley S.D.et.al.   12000953

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MIRFEDVSVT YDGATEPTVR AVDFEVPEGE LVLLAGPSGV GKSTVLGAVG GLVPHFTGGT 
61:	LRGRVTVAGR DTRTHKPREL ADVVGTVGQD PLSHFVTDTV EDELAYGMES LGLPPDVMRR 
121:	RVEETLDLLG LSDLRSRPIA TLSGGQQQRV AIGSVLTPHP DVLVLDEPTS ALDPAAAEEV 
181:	LAVLQRLVHD LGTTVLMAEH RLERVIQYAD QVVLLPAPGE APLIGAPAEV MAVSPVYPPV 
241:	VGLGRLAGWS PLPLTIRNAR RRAAPLRERL AGREIPDHTP PPSAPLPAPP APRPVTSRWR 
301:	RRGKRPENPS APTPYAAEVR SLAVRRDRVQ ALRHVDLTVS PGETVALMGR NGAGKSTLLS 
361:	ALVGLVEPSA GSVRAGDAVP HRTAPRDLVR RVGLVPQEPR DLLYADTVAA ECAAADRDAD 
421:	AAPGTCRALL SELLPGITDD IHPRDLSEGQ RLTLALSVVL TARPPLLLLD EPTRGLDYAA 
481:	KARLAGILRG LAAEGHAIVL ATHDVELAAE LAHRVVLLAE GEVIADGPAA DVVVASPSYA 
541:	PQVAKVLAPR KWLTVAQVRE ALT