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3.A.1.32.1
The putative cobalamin precursor uptake transporter, CbrTUV (Rodionov et al., 2009) (CbrT is most similar to 2.A.1.15.1; CbrU is most similar to 3.A.1.26.1 (MFS; e-4); CbrV is most similar to 2.A.53.11.1 and 3.A.1.2.2 (score of 0.035)) (CbrT has 6 putative TMSs; CbrV has 8-10 putative TMSs).

Accession Number:Q9KXJ7
Protein Name:Putative integral membrane protein
Length:379
Molecular Weight:39360.00
Species:Streptomyces coelicolor [1902]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Cobalamin

Cross database links:

HEGENOM: HBG696401
RefSeq: NP_626570.1   
Entrez Gene ID: 1097757   
Pfam: PF02361   
BioCyc: SCOE100226:SCO2323-MONOMER   
KEGG: sco:SCO2323   

Gene Ontology

GO:0015087 F:cobalt ion transmembrane transporter activity
GO:0009236 P:cobalamin biosynthetic process
GO:0006824 P:cobalt ion transport

References (1)

[1] “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).”  Bentley S.D.et.al.   12000953

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MGAGGTPSAP ASVPTPARHQ RRGALHPGAW WLWALGLGTA ATRTTNPLLL TLLVTVSAYV 
61:	VVTRRPHAPW SRSYGAFVKL ALAVLLIRLL FTTLLGSPIP GTHTLLTLPE VPLPDWAQGI 
121:	RLGGRVTAEG LTFALYDAMK LATLLICVGA ANALANPARL LKSLPGALYE MGVAVVVALT 
181:	FAPNLIADVQ RLRAARRLRG RPDRGVRGLL QVGLPVLEGA LERSVALAAA MDARGYGRTA 
241:	HVPAPVRRTT AALTLGGLLG VCAGTYGLLT AAGGTYGIPV LLAGVAAAVA GLWLGGRRTV 
301:	RTRYRPDRWD ARAWLVTASG ATVAALLFLA AARDPAALHP GVVPLEAPTL PLWPAAAVLV 
361:	GLLPAFITPV PEAAVKEPS