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1.A.1.4.2
K+channel, KDC1 (voltage and pH-dependent; inward rectifying). Does not form homomeric channels. The C-terminus functions in the formation of heteromeric complexes with other potassium alpha-subunits such as KAT1 (1.A.1.4.7) (Naso et al., 2009).

Accession Number:Q9SCF5
Protein Name:KDC1
Length:629
Molecular Weight:72278.00
Species:Daucus carota (Carrot) [4039]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

Pfam: PF00027    PF11834    PF00520   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005249 F:voltage-gated potassium channel activity
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “KDC1, a novel carrot root hair K+ channel. Cloning, characterization, and expression in mammalian cells.”  Downey P.et.al.   10970888

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAAETRSPVP LLYRRRSSGE IMRNMASVSS SLLPAFGTVV GDGSPLLRSY IIAPYDRRYR 
61:	WWQAFLVILV IYSAWSSPFE LAFKDVATGS LLPVDLVVDA FFAIDIILTF FVAYLDKSTY 
121:	LLVDDHKQIA VRYVTHLWFP MDLASTLPSQ TIYRIFAGEM HHGEVFGFLN LLRLWRLRRV 
181:	SELFSRLEKD TRFSYFWTRY CKLIAVTLFA VHSAACFYFW LAIHHKIPEQ TWIGAQVDNF 
241:	ENRSIWLGYT YAMYWSIVTL TTTGYGDLYS KNTGEKVFNI FYMLFNIGLT AYLIGNMTNL 
301:	IVHSAIKTFA MRDAINEVLR YASKNRLPEG LKEQMLAHMQ LKFKTAELQQ EEVLEDLPKA 
361:	IRSSIAQHLF HKTIENTYLF RDVSDDLISQ LVSEIKAEYF PPKVEIILQN EIPTDFYVIA 
421:	SGAVDVVTQK NGIEQFVTKL SSKEMFGDIG VIFNIPQPFT VRTRRLSQVI RISHHSFKDM 
481:	MQPHNEDGQK ILRNFILYLK GLQKEVLDEI PFLSDMLGDL NNEHSGLLDQ SQEIEPSNYD 
541:	QGENAQGSHV DSAFQSAYPI RLVIHGHHPD LETEDKGTGK LIHLPESMEG LLMLAEKKFG 
601:	KKGDIVLMED GSQVEDLDAL RENDHLYIF