TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.1.5.27
CNGC15 of 678 aas and 6 TMSs.  In Medicago truncatula, three such channels, CNGC15a, b and c, are required for nuclear calcium oscillations, spiking and subsequent symbiotic responses. These three channels form a complex with the potassium permeable channel, DMI1 (TC# 1.A.1.23.1), in the nuclear envelope.  They are expressed in flowers and pods, and mutants in these channels have decreased fertilization rates (Charpentier et al. 2016). 

Accession Number:Q9SL29
Protein Name:Putative cyclic nucleotide-gated ion channel 15
Length:678
Molecular Weight:78723.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ca2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGYGNSRSVR FQEDQEVVHG GESGVKLKFK INGTQINNVK MMSKGKFLKA KVLSRVFSED 
61:	LERVKTKILD PRGQTIRRWN KIFLIACLVS LFVDPLFFFL PVMRNEACIT IGVRLEVVLT 
121:	LIRSLADAFY IAQILIRFRT AYIAPPSRVF GRGELVIDSR KIAWRYLHKS FWIHLVAALP 
181:	LPQVLIWIII PNLRGSPMTN TKNVLRFIII FQYVPRMFLI FPLSRQIIKA TGVVTETAWA 
241:	GAAYNLMLYM LASHVLGACW YLLAVERQEA CWRHACNIEK QICQYRFFEC RRLEDPQRNS 
301:	WFEWSNITTI CKPASKFYEF GIFGDAVTST VTSSKFINKY FYCLWWGLKN LSSLGQNLAT 
361:	STYAGEILFA IIIATLGLVL FALLIGNMQT YLQSTTMRLE EWRIRRTDTE QWMHHRQLPP 
421:	ELRQAVRKYD QYKWLATRGV DEEALLISLP LDLRRDIKRH LCFDLVRRVP LFDQMDERML 
481:	DAICERLKPA LCTEGTFLVR EGDPVNEMLF IIRGHLDSYT TNGGRTGFFN SCLIGPGDFC 
541:	GEELLTWALD PRPVVILPSS TRTVKAICEV EAFALKAEDL QFVASQFRRL HTKQLRHKFR 
601:	FYSHQWRTWA ACFIQAAWRR HRKRKYKTEL RAKEEFHYRF EAATARLAVN GGKYTRSGSD 
661:	SGMMSSIQKP VEPDFSSE