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1.A.1.5.8
The non-selective cation transporter involved in germination, CNGC3 (Gobert et al., 2006; Zelman et al., 2012).

Accession Number:Q9SKD7
Protein Name:CNGC3
Length:706
Molecular Weight:81669.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate cations

Cross database links:

Genevestigator: Q9SKD7
eggNOG: KOG0498
HEGENOM: HBG599469
RefSeq: NP_001118537.1    NP_566075.1   
Entrez Gene ID: 819251   
Pfam: PF00520   
KEGG: ath:AT2G46430   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005516 F:calmodulin binding
GO:0030552 F:cAMP binding
GO:0030553 F:cGMP binding
GO:0005216 F:ion channel activity
GO:0006811 P:ion transport
GO:0055085 P:transmembrane transport

References (4)

[1] “Characterisation of a novel gene family of putative cyclic nucleotide- and calmodulin-regulated ion channels in Arabidopsis thaliana.”  Koehler C.et.al.   10341447
[2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMNPQRNKFV RFNGNDDEFS TKTTRPSVSS VMKTVRRSFE KGSEKIRTFK RPLSVHSNKN 
61:	KENNKKKKIL RVMNPNDSYL QSWNKIFLLL SVVALAFDPL FFYIPYVKPE RFCLNLDKKL 
121:	QTIACVFRTF IDAFYVVHML FQFHTGFITP SSSGFGRGEL NEKHKDIALR YLGSYFLIDL 
181:	LSILPIPQVV VLAIVPRMRR PASLVAKELL KWVIFCQYVP RIARIYPLFK EVTRTSGLVT 
241:	ETAWAGAALN LFLYMLASHV FGSFWYLISI ERKDRCWREA CAKIQNCTHA YLYCSPTGED 
301:	NRLFLNGSCP LIDPEEITNS TVFNFGIFAD ALQSGVVESR DFPKKFFYCF WWGLRNLSAL 
361:	GQNLKTSAFE GEIIFAIVIC ISGLVLFALL IGNMQKYLQS TTVRVEEMRV KRRDAEQWMS 
421:	HRMLPDDLRK RIRKYEQYKW QETKGVEEEA LLSSLPKDLR KDIKRHLCLK LLKKVPWFQA 
481:	MDDRLLDALC ARLKTVLYTE KSYIVREGEP VEDMLFIMRG NLISTTTYGG RTGFFNSVDL 
541:	VAGDFCGDLL TWALDPLSSQ FPISSRTVQA LTEVEGFLLS ADDLKFVATQ YRRLHSKQLR 
601:	HMFRFYSVQW QTWAACFIQA AWKRHCRRKL SKALREEEGK LHNTLQNDDS GGNKLNLGAA 
661:	IYASRFASHA LRNLRANAAA RNSRFPHMLT LLPQKPADPE FPMDET