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1.A.1.5.9
The cyclic nucleotide-gated K+ channel, Sp-tetraKCNG (2238 aas) (Galindo et al., 2007)

Accession Number:A3EYY6
Protein Name:Sp-tetraKCNG
Length:2238
Molecular Weight:253435.00
Species:Strongylocentrotus purpuratus [7668]
Number of TMSs:24
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

RefSeq: NP_001075433.1   
Entrez Gene ID: 574759   
Pfam: PF00027    PF00520    PF07885   
KEGG: spu:574759   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005249 F:voltage-gated potassium channel activity
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Sp-tetraKCNG: A novel cyclic nucleotide gated K(+) channel.”  Galindo B.E.et.al.   17254550

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAGRTVSLEL EEPETGGSSD RATISSQSQS CFLNPKNSRM QAWETLIIIS ILTTFSFDLF 
61:	LASFDSKIII LWIILYTCDI LYLMDIVMRF FLGYMKDGIL ISDSNKIKIH YLRTTFPIDL 
121:	FTILPTDLLA LVYPGLGSTN FWKWIATFRF FNRVFRIMRL NSYFDSRESK LGSNTALLRT 
181:	LKYTIVAAMV IHLTACGWYY LACTGWHGNE TPVCQNDSWA LSFNFGQDLD EASTGDSYVI 
241:	SLYWSVATAT STGYGDISAV NEKEKWFSIF AMLLGIVVFF GMILGGMASM LTNFDAQRAR 
301:	YTHRFNVIKD SLRDQSVPED LQKQVIGYYE YLWVRKKGVT DDSLINALPL TFHAEVSLSG 
361:	NKYILDKAPM FQGLSDGFLR MLSLEIKPSL YLPRQKIAGR NEICHDMYFI QRGEIEVLSA 
421:	DDDDTPIARL NHGKLFGEVS LIFSMPRTNT IRAAAHCDLL VLDKGDLQNV LLHYPEVAKK 
481:	LQDIADQRCD AEGLLEERVR AGEGIIPASK SLSRHGNPQN KHDSAYPLNS YEAFDMEDVE 
541:	SEWVTVHRGS VVMRTGRHLR ILWDDIQSLI TDTVVLPNSR FARLWELLVL LVTLVIAFLY 
601:	PYCASFIANQ NRNDEGTENL ILLTHMYLMD FVLVIDIVVR LRTAVTTPNG TFKDFHYIRD 
661:	HYVRSWGFVA DVVAILPLDL FCLLLPVGIQ RTHALYLLAL NRLIKCWRVP NYLQNLEQNL 
721:	DVNIGTIRFF KFVIYIALLS HWSACLWYLF ACPSGNDDGA QAAPAVDMPV DEVFTLPSHE 
781:	YIQSLYWAAA TMTSTGYGDI SAHSTIGRAI ALAAMLVGLL LYGYCLSSIA ATLANSDAPR 
841:	VGFQEKLFAA QDFMKKHNLT PDLQQRVVNY LSLVFRRHRG EAIPGGERVM HDMPIQLQQD 
901:	IAYQDVHETL SKVPLFKECD SNFLRMLALK LHVFIFMPGD VIVYQGDMGR EMYFIRRGTC 
961:	EVLSKDGNHV MSNIGPGQYF GEVGLIFGDY RTATVRAASY CELLMLKRVD LDRVLKFFPL 
1021:	IEKQFSDAAR NQGHLRELRD ASKVDKKPVE FTPGTVLEPE DDEDSEDMSL YPAATSLRPV 
1081:	DISIKIFDKK SEDFQEPFQE ISLLSRLFAK LLMSRAFIPN GTCFKRWEAI RVAVAILAAF 
1141:	TVTLQAAFLH MNIGLWVVTY GLDFICFVDM YLKFHTAFYN ESNVLVTHPL STAKHYLRTN 
1201:	FLIDVLACFP TELIAYALIG NFSEEAIHVY ALVRINRLLQ LYRVPLAFNY LESDVQNLTG 
1261:	NIRMMKFFFY MVLFIHMLAC MWYMNACPPV FKYPITGETF NGFITTNFHR CKNNSWTSKT 
1321:	DTSFDDQPIA AQYVTSMYWA SATGASVGYG DIHANSVSEM ILALFSMIVG IVFFGYIIAS 
1381:	VAASLANADA QRARYQEKLT AIARYLKDQR VEKSLAQHVD VYYNYMWLRT KGVEPDSLFD 
1441:	GLPLALKADV SLNLYQGIIN KVPLFTNTEI GFQKMLAMCI KPVYYLNREY IVRKHDFGKE 
1501:	MFFIHRGLVE VVSEDGSIVF DTMQAGRFFG EISLVFSCPR TASIRAQNNV DMFVLNKEDL 
1561:	DEVLTHYPSI KDQINKVAED RITAVRKRSE AKVDQASNTP NNSNNNSIKG SSFNSIEKSE 
1621:	NSTASASSSG HPSCSSTADN ASSQTKPEDG HSTGTAAAAS DNRSEPESPS VSSTAATRPR 
1681:	SAEPPPPSAA PMKPARQIPQ PNANNNASTG EGSGNNNNQG GNNASNTQSD PSAPDSSSST 
1741:	THVPTRYPMP FCCIRRDKNY LEALLHANRF VLNPDSPVVR NLARLTCVLA VATSWTIMYQ 
1801:	AFYQVQSMPF LIFSYVCECV FIFEIYIKFH VSNADEYGAL EKDFGKIYKS YLRKWSGFAQ 
1861:	DLIPTLPIEL FAFLAQGDKQ FAVLSFLRFR QVIRLMRVSQ FFDRWEQELN INILKVRLTK 
1921:	FLVLLLIIIH LFASIWYTIA CPLSNCKNGS WATMMGYTEN EPYIFYRYCD TIYWAVATLT 
1981:	STGYGDIHAY SVPELVFASM VMVFGKLLFG WVLGNIASTL ANEESGRVSY EERLAAVKDQ 
2041:	MKDMRLNSKL RNRVISYFDY LWARNKGIDQ SILFRDAPFC LQTDLSLDVA GDHLQKVALF 
2101:	READEAFLRA LSLMLKPVLF MPNDLIVRQG DVGDEMYFIC RGVVEELEVN SHSRVARVLE 
2161:	TGEFLDDINL LYDVPRRTSY RARTHVDVLS LSVHDLKSVL EQYPQVEAQI RRIGKELYGD 
2221:	YASSVNAQEN FPAKQTEV