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1.A.1.7.2
AtTPK4 two-pore K+ channel 4 (Becker et al., 2004). Asp86 and Asp200 are essential for K+ permeation as well as inward rectification (Marcel et al., 2010).  Reviewed by González et al. 2014.

Accession Number:Q6X308
Protein Name:Two-pore potassium channel 4
Length:284
Molecular Weight:32061.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

Genevestigator: Q6X308
eggNOG: KOG1418
RefSeq: NP_171752.1   
Entrez Gene ID: 837846   
Pfam: PF07885   
KEGG: ath:AT1G02510   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005267 F:potassium channel activity
GO:0006813 P:potassium ion transport

References (1)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEEENLLNEN LLHPNESSPE ETQVTTVSKS KWTILVLAMI LLLVYLTFGV CTYSFFRDQF 
61:	SGTETNLFVD AFYFSIVTFS TVGYGDIVPS TSTTKILTIV LVSTGVVFLD YLLNRVVSHV 
121:	LSLQENAILD RINKTRNRAI RDHIAEDGKI RLKWKLCLAF CAVGLCVGSG ALFLHVFERL 
181:	DWLDSVYLSV ISVTTVGYGD KTFKTVEGRG FAVFWLLLST IAMATLFLYL AEMRIDRTTV 
241:	MKLPPSESEF IVFKLRESGR ISEDDIKQIV REFENLEEVP SSGS