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1.A.11.1.5
Ammonia channel (Ammonia transporter)

Accession Number:O66515
Protein Name:Ammonia channel
Length:423
Molecular Weight:44323.00
Species:Aquifex aeolicus (strain VF5) [224324]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ammonia

Cross database links:

eggNOG: COG0004
HEGENOM: HOG000017736
Entrez Gene ID: 1192526   
Pfam: PF00909   
KEGG: aae:aq_112   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008519 F:ammonium transmembrane transporter activity

References (2)

[1] “The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.”  Deckert G.et.al.   9537320
[2] “Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.”  Khademi S.et.al.   15361618

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRALGFIGII LSIFSSFAYA SEAKLDTGNT AWMLVASALV VFMTVPGLAL FYGGLDKSKS 
61:	ILNTIAMSFS AFAVVTLTWI FVGYSVAYGD DIFGFIGNPF QYVLGKGISG INSDTGYPAL 
121:	LDLMFQLTFA TITTALISGS FVGRMKFSAW ILFAILWSVF VYPPVAHWVW GGGFLANDGA 
181:	LDFAGGTVVH INAGIAGLVG ALILGRRKDT SLIPNNVPLV ALGAGILWFG WFGFNAGSAL 
241:	GANESAAWAM INTTVATSTA ALAWMFTEWL HVGKPTVVGI SSGIVAGLVA ITPAAGFVNL 
301:	IGSIFIGAIA SVCAYFMVAL VKPKFGYDDA LDVFGIHGVR GIVGAVLTGV FADPNVGGTP 
361:	GLLYGNPKQV LIQIEGVIAT ILYSAILTAV ILLVLKAVVG LRVSEEEELE LDSSLHGEKA 
421:	YNL