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1.A.11.2.7
Amt2 NH4+/CH3-NH3+ transporter, subject to allosteric activation by a C-terminal region (Loqué et al., 2009).

Accession Number:O28528
Protein Name:Ammonium transporter (Amt-2)
Length:468
Molecular Weight:49591.00
Species:Archaeoglobus fulgidus [2234]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate NH4+, Methylammonium

Cross database links:

HEGENOM: HBG677626
RefSeq: NP_070574.1   
Entrez Gene ID: 1484969   
Pfam: PF00909   
BioCyc: AFUL224325:AF_1746-MONOMER   
KEGG: afu:AF1746   

Gene Ontology

GO:0016020 C:membrane
GO:0008519 F:ammonium transmembrane transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus.”  Klenk H.-P.et.al.   9389475

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVGRMCVAVL IVLLLVATAG ADPNGAETLK ENPELPVDFV WALICGFLVM FMQAGFAMLE 
61:	AGFSRAKNVA NVMMKNLMDF AVGSLAFFAV GFALMMGADW QGIAGTTGWF LAGESYDVST 
121:	IELWFFMLVF AATAATIVSG SIAERPKFSV YLVYSAVVSA VIYPIYGHWL WGGGWLSSSE 
181:	FMVKLGGGYG ALDFAGSGVV HALGGYIALA AVMLLGPRLG KYDSDGNPRA IPGHNLAFAV 
241:	IGTFILWFGW FGFNAGSTLS AHELRVSIIA SNTNLAAAAG AVTAMAITWL RNGKPDVGMT 
301:	CNGAVAGLVA ITAPCAWVQP WSSVVIGTIA GFIATYGYWW LEKRGLDDVV GAIPVHGFSG 
361:	TWGLIALGIF ADGSYGLYAT ESPLVTGLLY GNWGFFIVQL ISAIVNFAWA FGTGFALFWI 
421:	LKKVIGIRVS PEEEMLGLDI AEHAAVAYPN FVCTETELPL AMKQGGGR