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1.A.11.2.9
Ammonium transporter 2, AmtB

Accession Number:Q9BLG3
Protein Name:Ammonium transporter 2
Length:431
Molecular Weight:46368.00
Species:Dictyostelium discoideum (Slime mold) [44689]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NH4+

Cross database links:

eggNOG: COG0004
Entrez Gene ID: 8621332   
Pfam: PF00909   
KEGG: ddi:DDB_G027788   

Gene Ontology

GO:0031164 C:contractile vacuolar membrane
GO:0010008 C:endosome membrane
GO:0016021 C:integral to membrane
GO:0005765 C:lysosomal membrane
GO:0030670 C:phagocytic vesicle membrane
GO:0005886 C:plasma membrane
GO:0008519 F:ammonium transmembrane transporter activity

References (4)

[1] “Regulation of ammonia homeostasis by the ammonium transporter AmtA in Dictyostelium discoideum.”  Yoshino R.et.al.   17951519
[2] “The genome of the social amoeba Dictyostelium discoideum.”  Eichinger L.et.al.   15875012
[3] “Temporal and spatial expression of ammonium transporter genes during growth and development of Dictyostelium discoideum.”  Follstaedt S.C.et.al.   14686953
[4] “Subcellular localization of ammonium transporters in Dictyostelium discoideum.”  Kirsten J.H.et.al.   19108721

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEYLELNGTK EGLSAAVDDM WVLNATYLVF YMQAGFCMLE AGVVRAKNAK SIIMKSIIDT 
61:	AIGSLLFWAL GFGLAFGNAD KASNPVIGTS HFFLINYQNL SFFAFQWAFC ATSITIVSGS 
121:	LAERVHVTSC LVYTIVMSAF IYPLSAHWVW SYNGWLRMIG FNGIIDFSGS IVVHIVGGCI 
181:	GLVGTYLVGP RIGRFDSESG KPKPLPGHSI TIYTLGAFII WYGFYGFNTG STLGISGGGI 
241:	AIASRSAVTM TIIACASCAT TLLAIKIKSG KYDVVKSVNS LLGGLVSSAA VCSLIDPWAA 
301:	FIIGCVTSFV YLGCSHLLIK LRIDDPLDSS AIHLGCGIWG ALSVGLFSTQ ENLSLVLKKS 
361:	TNVYGLFFGG GFEQLGIQLL GIIIVMAWCF FCASILFTIL KKFHLLRIEP TKELMGIDID 
421:	SAGGPAYQWD N