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1.A.11.3.5
The Mep2 ammonium transporter 60% identical to the S. cerevisiae Mep2 (1.A.11.3.2). (Distinct residues mediate transport and signaling; Dabas et al., 2009).

Accession Number:Q59UP8
Protein Name:Putative uncharacterized protein MEP2
Length:480
Molecular Weight:51912.00
Species:Candida albicans (Yeast) [5476]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NH4+

Cross database links:

RefSeq: XP_713353.1    XP_713400.1   
Entrez Gene ID: 3644964    3645022   
Pfam: PF00909   
KEGG: cal:CaO19.13117    cal:CaO19.5672   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008519 F:ammonium transmembrane transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “The diploid genome sequence of Candida albicans.”  Jones T.et.al.   15123810

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSGNFTGTGT GGDVFKVDLN EQFDRADMVW IGTASVLVWI MIPGVGLLYS GISRKKHALS 
61:	LMWAALMAAC VAAFQWFWWG YSLVFAHNGS VFLGTLQNFC LKDVLGAPSI VKTVPDILFC 
121:	LYQGMFAAVT AILMAGAGCE RARLGPMMVF LFIWLTVVYC PIAYWTWGGN GWLVSLGALD 
181:	FAGGGPVHEN SGFAALAYSL WLGKRHDPVA KGKVPKYKPH SVSSIVMGTI FLWFGWYGFN 
241:	GGSTGNSSMR SWYACVNTNL AAATGGLTWM LVDWFRTGGK WSTVGLCMGA IAGLVGITPA 
301:	AGYVPVYTSV IFGIVPAIIC NFAVDLKDLL QIDDGMDVWA LHGVGGFVGN FMTGLFAADY 
361:	VAMIDGTEID GGWMNHHWKQ LGYQLAGSCA VAAWSFTVTS IILLAMDRIP FLRIRLHEDE 
421:	EMLGTDLAQI GEYAYYADDD PETNPYVLEP IRSTTISQPL PHIDGVADGS SNNDSGEAKN