TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.11.4.4
The RH50 NH3 channel (most like human Rh proteins TC# 1.A.11.4.1 and 2; 36-38% identity) (Cherif-Zahar et al., 2007). The Rh CO2 channel protein (3-D structure ± CO2 available) (3B9Z_A; 3B9Y_A) (Li et al., 2007; Lupo et al., 2007) (also transports methyl ammonia) (Weidinger et al., 2007).

Accession Number:Q82X47
Protein Name:Ammonium transporter family
Length:425
Molecular Weight:44618.00
Species:Nitrosomonas europaea [915]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Secreted1
Substrate ammonia, Methylammonia

Cross database links:

HEGENOM: HBG713085
DIP: DIP-29966N
RefSeq: NP_840535.1   
Entrez Gene ID: 1081386   
Pfam: PF00909   
BioCyc: NEUR228410:NE0448-MONOMER   
KEGG: neu:NE0448   

Gene Ontology

GO:0016020 C:membrane
GO:0008519 F:ammonium transmembrane transporter activity
GO:0055085 P:transmembrane transport

References (2)

[1] “Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea.”  Chain P.et.al.   12700255
[2] “Evolutionary conservation and diversification of Rh family genes and proteins.”  Huang C.-H.et.al.   16227429
Structure:
3B9W   3B9Y   3B9Z   3BHS     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSKHLCFTAF SSIALFLLCF SSWASAVAPA EINEARLVAQ YNYSINILAM LLVGFGFLMV 
61:	FVRRYGFSAT TGTYLVVATG LPLYILLRAN GIFGHALTPH SVDAVIYAEF AVATGLIAMG 
121:	AVLGRLRVFQ YALLALFIVP VYLLNEWLVL DNASGLTEGF QDSAGSIAIH AFGAYFGLGV 
181:	SIALTTAAQR AQPIESDATS DRFSMLGSMV LWLFWPSFAT AIVPFEQMPQ TIVNTLLALC 
241:	GATLATYFLS ALFHKGKASI VDMANAALAG GVAIGSVCNI VGPVGAFVIG LLGGAISVVG 
301:	FVFIQPMLES KAKTIDTCGV HNLHGLPGLL GGFSAILIVP GIAVAQLTGI GITLALALIG 
361:	GVIAGALIKL TGTTKQAYED SHEFIHLAGP EDEHKAERLV LEAKTEIQGL KNRIDAAVLS 
421:	AKSEG