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1.A.11.4.6
Rhesus-like glycoprotein A (Rh50-like protein RhgA)

Accession Number:Q9NIV0
Protein Name:Rhesus-like glycoprotein A
Length:527
Molecular Weight:58360.00
Species:Dictyostelium discoideum (Slime mold) [44689]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Contractile vacuole1
Substrate Unknown

Cross database links:

eggNOG: NOG276393
Entrez Gene ID: 8624067   
Pfam: PF00909   
KEGG: ddi:DDB_G028338   

Gene Ontology

GO:0000331 C:contractile vacuole
GO:0016021 C:integral to membrane
GO:0008519 F:ammonium transmembrane transporter activity

References (5)

[1] “Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.”  Liu Z.et.al.   10852913
[2] “The genome of the social amoeba Dictyostelium discoideum.”  Eichinger L.et.al.   15875012
[3] “Localization of the Rh50-like protein to the contractile vacuole in Dictyostelium.”  Benghezal M.et.al.   11220631
[4] “Acidic clusters target transmembrane proteins to the contractile vacuole in Dictyostelium cells.”  Mercanti V.et.al.   16478785
[5] “High-throughput analysis of spatio-temporal dynamics in Dictyostelium.”  Sawai S.et.al.   17659086

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTHNDDDHKW VTTKRKEPIF FTVILFIFQI FMIICFAALT GYDTNKNYTG SENPDEFKGG 
61:	EVQERVNNFY GYFRDINIMI FFGFGFLMTF LRRYGYSALG YTFIISALVS QWSVLLNGFF 
121:	EAWSHSNKHG EFPSTWEFSM DSLLQGFFCS GSVMISYGAI LGRVTPLHML IMGIIEPIFF 
181:	FLNVFIGEMN LEAIDVGGGM YIHLFGSVFG LTVAWFLTDR KSKECTDNAP SYSGDNFAMA 
241:	GTLFLWMMWP SFNAAIAPLG EPQFRAIANT FLSLTGSTVA TFIVSRLFSH LGNKLDMVHV 
301:	QNSSLAGGVV QGCIAHMNIN PGGAIAMGFI AGTISVCGYL FITPKVQRKL HIQDTCGILN 
361:	LHCIPGFLGS IAAIFAAIKG LNNPNMYSKV EFEQIFRAGD SQASANLIAT MVSIGLGIVG 
421:	GLLVGVILLQ LKKIKGLKSK EYYQDSAFWI LPIDYPKDVA TVVALNNAAT SEDTAGGDDE 
481:	EEGVGKEHGA VEMGKHNRIV QPKQDNKYHK QLPSDDEEED EFKQEPI