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1.A.12.1.3
Organellar chloride channel, CLIC-5A (251 aas; 2 TMSs; one of six homologous human genes) (95% identical to 1.A.12.1.1 but lacks the N-terminal 185 residues.) It associates with the cortical actin cytoskeleton (Berryman et al., 2004).

Accession Number:Q53G01
Protein Name:Chloride intracellular channel 5 variant
Length:251
Molecular Weight:28179.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

RefSeq: NP_001107558.1    NP_058625.2   
Entrez Gene ID: 53405   
KEGG: hsa:53405   

Gene Ontology

GO:0016020 C:membrane
GO:0005247 F:voltage-gated chloride channel activity
GO:0006821 P:chloride transport

References (2)

[1] “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.”  Maruyama K.et.al.   8125298
[2] “Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.”  Suzuki Y.et.al.   9373149

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTDSATANGD DRDPEIELFV KAGIDGESIG NCPFSQRLFM ILWLKGVVFN VTTVDLKRKP 
61:	ADLHNLAPGT HPPFLTFNGD VKTDVNKIEE FLEETLTPEK YPKLAAKHRE SNTAGIDIFS 
121:	KFSAYIKNTK QQNNAALERG LTKALKKLDD YLNTPLPEEI DANTCGEDKG SRRKFLDGDE 
181:	LTLADCNLLP KLHVVKIVAK KYRNYDIPAE MTGLWRYLKN AYARDEFTNT CAADSEIELA 
241:	YADVAKRLSR S