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1.A.12.2.1
The plant Cl- intracellular channel protein DHAR1 (glutathione dehydrogenase/dehydroascorbate reductase) (Elter et al., 2007)

Accession Number:Q9FWR4
Protein Name:GSH-dependent dehydroascorbate reductase 1
Length:213
Molecular Weight:23641.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Location1 / Topology2 / Orientation3: Mitochondrion1
Substrate Cl-

Cross database links:

Genevestigator: Q9FWR4
eggNOG: KOG1422
HEGENOM: HBG319818
RefSeq: NP_001077564.1    NP_173387.1   
Entrez Gene ID: 838544   
Pfam: PF00043    PF02798   
KEGG: ath:AT1G19570   

Gene Ontology

GO:0048046 C:apoplast
GO:0009570 C:chloroplast stroma
GO:0005739 C:mitochondrion
GO:0005777 C:peroxisome
GO:0005886 C:plasma membrane
GO:0005773 C:vacuole
GO:0005507 F:copper ion binding
GO:0045174 F:glutathione dehydrogenase (ascorbate) activity
GO:0004364 F:glutathione transferase activity
GO:0006952 P:defense response
GO:0010731 P:protein amino acid glutathionylation
GO:0043903 P:regulation of symbiosis, encompassing mutua...
GO:0009753 P:response to jasmonic acid stimulus
GO:0010193 P:response to ozone
GO:0009610 P:response to symbiotic fungus
GO:0010043 P:response to zinc ion

References (10)

[1] “Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.”  Dixon D.P.et.al.   12077129
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Functional annotation of a full-length Arabidopsis cDNA collection.”  Seki M.et.al.   11910074
[4] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[5] “Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.”  Chew O.et.al.   12954611
[6] “A conserved transcript pattern in response to a specialist and a generalist herbivore.”  Reymond P.et.al.   15494554
[7] “Stress-induced protein S-glutathionylation in Arabidopsis.”  Dixon D.P.et.al.   16055689
[8] “Cytosolic dehydroascorbate reductase is important for ozone tolerance in Arabidopsis thaliana.”  Yoshida S.et.al.   16361320
[9] “Coordinated activation of metabolic pathways for antioxidants and defence compounds by jasmonates and their roles in stress tolerance in Arabidopsis.”  Sasaki-Sekimoto Y.et.al.   16262714
[10] “Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry.”  Kung C.-C.S.et.al.   16526091

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALEICVKAA VGAPDHLGDC PFSQRALLTL EEKSLTYKIH LINLSDKPQW FLDISPQGKV 
61:	PVLKIDDKWV TDSDVIVGIL EEKYPDPPLK TPAEFASVGS NIFGTFGTFL KSKDSNDGSE 
121:	HALLVELEAL ENHLKSHDGP FIAGERVSAV DLSLAPKLYH LQVALGHFKS WSVPESFPHV 
181:	HNYMKTLFSL DSFEKTKTEE KYVISGWAPK VNP