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1.A.13.2.3
The YfbK/CaClC homologue of 575aas and 0 TMSs.  YfbK has amyloidogenic regions due to asparagine- and glutamine-rich regions which is a common feature of many known amyloid proteins. This correlates with detergent-induced denaturation resistance (Antonets et al. 2016).

Accession Number:P76481
Protein Name:Uncharacterized protein yfbK
Length:575
Molecular Weight:63634.00
Species:Escherichia coli (strain K12) [83333]
Substrate Unknown, Cl-

Cross database links:

Genevestigator: P76481
EchoBASE: EB3848
EcoGene: EG14095
eggNOG: COG2304
HEGENOM: HBG503062
Entrez Gene ID: 946743   
Pfam: PF12034    PF00092    PF12450   
KEGG: ecj:JW2265    eco:b2270   

References (2)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRNKNIIMLL MSSLILSGCG PQPENKESQQ QQPSTPTEQQ VLAAQQAAIK EAEQSAAAAK 
61:	ALAQQEVQQY SDKQALQGRL QEAPTFARAA KAKATHIANP GTARYQQFDD NPVKQVAQNP 
121:	LATFSLDVDT GSYANVRRFL NQGLLPPPDA VRVEEIVNYF PSDWDIKDKQ SIPASKPIPF 
181:	AMRYELAPAP WNEQRTLLKV DILAKDRKSE ELPASNLVFL IDTSGSMISD ERLPLIQSSL 
241:	KLLVKELREQ DNIAIVTYAG DSRIALPSIS GSHKAEINAA IDSLDAEGST NGGAGLELAY 
301:	QQATKGFIKG GINRILLATD GDFNVGIDDP KSIESMVKKQ RESGVTLSTF GVGNSNYNEA 
361:	MMVRIADVGN GNYSYIDTLS EAQKVLNSEM RQMLITVAKD VKAQIEFNPA WVTEYRQIGY 
421:	EKRQLRVEHF NNDNVDAGDI GAGKHITLLF ELTLNGQKAS IDKLRYAPDN KLAKSDKTKE 
481:	LAWLKIRWKY PQGKESQLVE FPLGPTINAP SEDMRFRAAV AAYGQKLRGS EYLNNTSWQQ 
541:	IKQWAQQAKG EDPQGYRAEF IRLIELADGV TDISQ