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1.A.14.3.5
The BH3-only protein, Ynl205c (Büttner et al., 2011)

Accession Number:P48558
Protein Name:Uncharacterized vacuolar membrane protein YNL305C
Length:297
Molecular Weight:33645.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P48558
eggNOG: COG0670
HEGENOM: HBG595196
Entrez Gene ID: 855411   
Pfam: PF01027   
KEGG: sce:YNL305C   

Gene Ontology

GO:0005783 C:endoplasmic reticulum
GO:0000324 C:fungal-type vacuole
GO:0016021 C:integral to membrane
GO:0005739 C:mitochondrion
GO:0005774 C:vacuolar membrane
GO:0006915 P:apoptotic process
GO:0019722 P:calcium-mediated signaling
GO:0030968 P:endoplasmic reticulum unfolded protein response

References (5)

[1] “Sequence analysis of a 30 kb DNA segment from yeast chromosome XIV carrying a ribosomal protein gene cluster, the genes encoding a plasma membrane protein and a subunit of replication factor C, and a novel putative serine/threonine protein kinase gene.”  Maurer K.C.T.et.al.   8553702
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.”  Philippsen P.et.al.   9169873
[3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[4] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[5] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGPPPPYEE QSSHLYGQPA SSQDGNAFIP EDFKYSTVVI SCEPIIRQRF MHKVYSLLSC 
61:	QLLASLSFCY WASVSTSLQN FIMSHIALFY ICMVVSLVSC IWLAVSPRPE DYEASVPEPL 
121:	LTGSSEEPAQ EQRRLPWYVL SSYKQKLTLL SIFTLSEAYC LSLVTLAYDK DTVLSALLIT 
181:	TIVVVGVSLT ALSERFENVL NSATSIYYWL NWGLWIMIGM GLTALLFGWN THSSKFNLLY 
241:	GWLGAILFTA YLFIDTQLIF RKVYPDEEVR CAMMLYLDIV NLFLSILRIL ANSNDDN