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1.A.15.1.1
Sec62 of 274 aas and 2, 3 or 4  putative TMSs (Lyman and Schekman 1997).

Accession Number:P21825
Protein Name:Translocation protein SEC62
Length:274
Molecular Weight:31347.00
Species: [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P21825
eggNOG: fuNOG08725
HEGENOM: HBG395377
DIP: DIP-3827N
RefSeq: NP_015231.2   
Entrez Gene ID: 856011   
Pfam: PF03839   
KEGG: sce:YPL094C   

Gene Ontology

GO:0030176 C:integral to endoplasmic reticulum membrane
GO:0031207 C:Sec62/Sec63 complex
GO:0005515 F:protein binding
GO:0008565 F:protein transporter activity
GO:0031204 P:posttranslational protein targeting to memb...

References (8)

[1] “SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum.”  Deshaies R.J.et.al.   2687286
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.”  Bussey H.et.al.   9169875
[3] “Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.”  Deshaies R.J.et.al.   2000150
[4] “Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.”  Panzner S.et.al.   7758110
[5] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[6] “Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum.”  Plath K.et.al.   14617809
[7] “Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.”  Willer M.et.al.   12518317
[8] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

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Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSAVGPGSNA GASVNGGSAT AIATLLRNHK ELKQRQGLFQ AKQTDFFRYK RFVRALHSEE 
61:	YANKSARQPE IYPTIPSNKI EDQLKSREIF IQLIKAQMVI PVKKLHSQEC KEHGLKPSKD 
121:	FPHLIVSNKA QLEADEYFVW NYNPRTYMDY LIVIGVVSII LALVCYPLWP RSMRRGSYYV 
181:	SLGAFGILAG FFAVAILRLI LYVLSLIVYK DVGGFWIFPN LFEDCGVLES FKPLYGFGEK 
241:	DTYSYKKKLK RMKKKQAKRE SNKKKAINEK AEQN