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1.A.16.3.3
Hydrosulfide (hydrogen sulfide; HS-), Fnt3 (Hsc) channel.  Also probably transports chloride, formate and nitrite. The 3-d crystal structure (2.2Å resolution in the closed state) is known (PDB# 3TE2) (Czyzewski and Wang, 2012). The Fnt3 gene is linked to the asrABC operon encoding the sulfite (SO32-) reductase that gives HS- as the product (Czyzewski and Wang 2012).

Accession Number:Q186B7
Protein Name:Putative formate/nitrite transporter
Length:258
Molecular Weight:27231.00
Species:Clostridium difficile (strain 630) [272563]
Number of TMSs:6
Substrate Hydrosulfide

Cross database links:

Structure:
3TDO   3TDP   3TDR   3TDS   3TDX   3TE0   3TE1   3TE2     

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHKETLDKLT NAAINKINLL NTSKVKYLVS SAFAGLYVGI GILLIFTIGG LLTDAGSPMT 
61:	KIVMGLSFAI ALSLVIMTGT ELFTGNNMVM SAGMLNKGVS IKDTSKIWAY SWVGNLIGAL 
121:	VLGIIFVGTG LVDKGPVAEF FANTAASKAS MPFTALFFRG ILCNILVCVS VLCSFRTNSD 
181:	TAKIIMIFLC LFAFITSGFE HSVANMTIYS VSLFSPTIST VTIGGAIYNL VAVTLGNIVG 
241:	GALFMGLGTY ILGKEKLN