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1.A.17.5.12
The osmosensitive calcium-permeable cation channel, CSC1 of 806 aas.  Activated by hyperosmolarity and Ca2+ (Hou et al. 2014).

Accession Number:Q9P1W3
Protein Name:Calcium permeable stress-gated cation channel 1
Length:806
Molecular Weight:93317.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ca2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSASPDDLST GGRLQNMTVD ECFQSRNTVL QGQPFGGVPT VLCLNIALWV LVLVVYSFLR 
61:	KAAWDYGRLA LLIHNDSLTS LIYGEQSEKT SPSETSLEME RRDKGFCSWF FNSITMKDED 
121:	LINKCGDDAR IYIVFQYHLI IFVLIICIPS LGIILPINYT GSVLDWSSHF ARTTIVNVST 
181:	ESKLLWLHSL LSFFYFITNF MFMAHHCLGF APRNSQKVTR TLMITYVPKD IEDPELIIKH 
241:	FHEAYPGSVV TRVHFCYDVR NLIDLDDQRR HAMRGRLFYT AKAKKTGKVM IRIHPCARLC 
301:	FCKCWTCFKE VDAEQYYSEL EEQLTDEFNA ELNRVPLKRL DLIFVTFQDS RMAKRVRKDY 
361:	KYVQCGVQPQ QSSVTTIVKS YYWRVTMAPH PKDIIWKHLS VRRFFWWARF IAINTFLFFL 
421:	FFFLTTPAII MNTIDMYNVT RPIEKLQNPI VTQFFPSVML WGFTVILPLI VYFSAFLEAH 
481:	WTRSSQNLVM VHKCYIFLVF MVVILPSMGL TSLDVFLRWL FDIYYLEQAS IRFQCVFLPD 
541:	NGAFFVNYVI TAALLGTGME LLRLGSLFCY STRLFFSRSE PERVNIRKNQ AIDFQFGREY 
601:	AWMMNVFSVV MAYSITCPII VPFGLLYLCM KHLTDRYNMY YSFAPTKLNE QIHMAAVSQA 
661:	IFAPLLGLFW MLFFSILRLG SLHAITIFSL STLLIAMVIA FVGIFLGKLR MVADYEPEEE 
721:	EIQTVFDMEP SSTSSTPTSL LYVATVLQEP ELNLTPASSP ARHTYGTMNN QPEEGEEESG 
781:	LRGFARELDS AQFQEGLELE GQNQYH