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1.A.2.1.4
Hepatocyte basolateral inwardly rectifying K+ channel, Kir4.2, involved in bile secretion (Hill et al., 2002)

Accession Number:Q91ZF1
Protein Name:ATP-sensitive inward rectifier potassium channel 15 aka Kcnj15 aka Kir4.2
Length:405
Molecular Weight:45908.00
Species:Rattus norvegicus (Rat) [10116]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

Genevestigator: Q91ZF1
eggNOG: maNOG07397
RefSeq: NP_579855.1   
Entrez Gene ID: 170847   
Pfam: PF01007   
KEGG: rno:170847   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005242 F:inward rectifier potassium channel activity
GO:0006813 P:potassium ion transport

References (1)

[1] “Cloning, expression, and localization of a rat hepatocyte inwardly rectifying potassium channel.”  Hill C.E.et.al.   11804844

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVARWVKGSE DAPLALQKIP DLQSGPRSLR MEAIHIGMSS APLVKHSNGV GLKAHRPRVM 
61:	SKSGHSNVRI DKVDGIYLLY LQDLWTTVID MKWRYKLTLF AATFVMTWFL FGVVYYAIAF 
121:	IHGDLELGES NSNHTPCIMK VDSLTGAFLF SLESQTTIGY GVRSITEECP HAIFLLVAQL 
181:	VITTLIEIFI TGTFLAKIAR PKKRAETIKF SHCAVISKQN GKLCLVIQVA NMRKSLLIQC 
241:	QLSGKLLQTH VTKEGERILL NQATVKFHVD SSSESPFLIL PMTFYHVLDE TSPLRDLTPQ 
301:	NLKEKEFELV VLLNATVEST SAVCQSRTSY IPEEIYWGFE FVPVVSLSKN GKYVADFSQF 
361:	EQIRKSPDCT FYCADSEKQK LEEQYRQEDQ RERELRSLLL QQSNV