TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.2.1.6
ATP-sensitive K+ channel, Kir6.3 (Zhang et al., 2005)

Accession Number:Q5R205
Protein Name: Potassium inwardly-rectifying channel, subfamily J, member 11 aka Kir6.3 aka kcnj11l
Length:432
Molecular Weight:48253.00
Species:Danio rerio (Zebrafish) (Brachydanio rerio) [7955]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

eggNOG: fiNOG05250
HEGENOM: HBG716702
RefSeq: NP_001012387.1   
Entrez Gene ID: 497647   
Pfam: PF01007   
KEGG: dre:497647   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005622 C:intracellular
GO:0005886 C:plasma membrane
GO:0005242 F:inward rectifier potassium channel activity
GO:0006813 P:potassium ion transport

References (1)

[1] “Identification and characterization of a novel member of the ATP-sensitive K+ channel subunit family, Kir6.3, in zebrafish.”  Zhang C.et.al.   16317080

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLARKGLLPD GFLLTRLAED AQPSRIRPKS QRARFITKSG SCNVAHKNIR EQGRFLQDVF 
61:	TTMVDLKWQH SLLIFTSAFL CSWMLFAMVW WLLAFAHGDL EPRDPNEPGP VPCVTSIHSF 
121:	TSAFLFSIEV QVTIGFGGRM VTEECPLAII VLIIQNILGL IINAIMLGCV FMKTAQANRR 
181:	AETLIFSRNA VIAPRNGRPT LMFRVGDLRK SMIISANIQL QVIRRTVTAE GEVIPVCQLD 
241:	IQVENPLRSN GIFLVSPLII SHTIDRGSPL YELSAQSMAT EDLEIIVILE GVVETTGITM 
301:	QARTSYIPEE ILWGRRFVSI MTEEDGRYSV DYSKFGNTVP VRMPALSAKE LDQTRGVQDS 
361:	GPHEGKPQGW GLVRAGRGGY RRGGARACDD TAAKPWYVPA EKEEEKKGQK KTVKLEEIGR 
421:	EIEEETTEDM SD