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1.A.21.1.4
The BH3-only (Mcl-1) protein (mediates apoptosis). (3-d strucure known)

Accession Number:B4DG83
Protein Name:cDNA FLJ50136, highly similar to Induced myeloid leukemia cell differentiation protein Mcl-1
Length:240
Molecular Weight:26420.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:2
Substrate cytochrome c

Cross database links:

Pfam: PF00452   

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEAPAADAIM SPEEELDGYE PEPLGKRPAV LPLLELVGES GNNTSTDGSL PSTPPPAEEE 
61:	EDELYRQSLE IISRYLREQA TGAKDTKPMG RSGATSRKAL ETLRRVGDGV QRNHETAFQG 
121:	MLRKLDIKNE DDVKSLSRVM IHVFSDGVTN WGRIVTLISF GAFVAKHLKT INQESCIEPL 
181:	AESITDVLVR TKRDWLVKQR GWDGFVEFFH VEDLEGGIRN VLLAFAGVAG VGAGLAYLIR