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1.A.21.1.5
Pro-survival Bcl-w protein.  Binds the BH3-only protein Bop to inhibit Bop-induced apoptosis (Zhang et al. 2012).  The structure is known (PDB# 1MK3).

Accession Number:Q92843
Protein Name:Bcl-2-like protein 2
Length:193
Molecular Weight:20746.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Peripheral membrane protein2
Substrate cytochrome c

Cross database links:

Structure:
1MK3   1O0L   1ZY3   2Y6W   4CIM     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT 
61:	FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG 
121:	QVQEWMVAYL ETQLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RTVLTGAVAL 
181:	GALVTVGAFF ASK