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1.A.22.1.3
MscL; catalyzes ion and osmolyte release following osmmotic downshift

Accession Number:P94585
Protein Name:MscL
Length:130
Molecular Weight:14280.00
Species:Bacillus subtilis [1423]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ions, Osmolytes

Cross database links:

HEGENOM: HBG727604
RefSeq: NP_391517.1   
Entrez Gene ID: 936909   
Pfam: PF01741   
KEGG: bsu:BSU36360   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005216 F:ion channel activity
GO:0006811 P:ion transport

References (2)

[1] “The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).”  Presecan E.et.al.   9353933
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MWNEFKAFAM RGNIVDLAIG VVIGGAFGKI VTSLVNDIIM PLVGLLLGGL DFSGLSFTFG 
61:	DAVVKYGSFI QTIVNFLIIS FSIFIVIRTL NGLRRKKEAE EEAAEEAVDA QEELLKEIRD 
121:	LLKQQAKSPE