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1.A.22.1.7
Large-conductance mechanosensitive channel, MscL

Accession Number:Q5N075
Protein Name:Large-conductance mechanosensitive channel
Length:133
Molecular Weight:14398.00
Species:Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) [269084]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

eggNOG: COG1970
HEGENOM: HOG000226782
Entrez Gene ID: 3199224   
Pfam: PF01741   
KEGG: syc:syc2105_d   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005216 F:ion channel activity

References (1)

[1] “Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization.”  Sugita C.et.al.   17211581

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSRRGRAVG FIRDFQAFIL KGNVVELAVA VIIGGAFNKI VSSFVGDLVM PLVNPLIPGG 
61:	DWRTAVIGPG LKIGSFAGSV IDFLIIAFVL YLAIRAIERF KRKEEAVVAA AEPDVQQQML 
121:	ATLERIADNL EAR