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1.A.23.3.1
The YkuT osmolyte efflux channel

Accession Number:O34897
Protein Name:TkuT
Length:267
Molecular Weight:29956.00
Species:Bacillus subtilis [1423]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Osmolytes

Cross database links:

HEGENOM: HBG728528
RefSeq: NP_389304.2   
Entrez Gene ID: 938809   
Pfam: PF00924   
BioCyc: SUBTI:BSU14210-MONOMER   
KEGG: bsu:BSU14210   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (4)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[3] “Responses of Bacillus subtilis to hypotonic challenges: physiological contributions of mechanosensitive channels to cellular survival.”  Hoffmann T.et.al.   18310427
[4] “Growth, osmotic downshock resistance and differentiation of Bacillus subtilis strains lacking mechanosensitive channels.”  Wahome P.G.et.al.   17665170

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDFIKQYDWA GLITNAGVLL IKLAIMILLY FIVRSLGMKI IKHLFAKFEE QNSLSIGRAH 
61:	TLRSLTLNIF AYTLIFIFFV MVLDLFHYDP SALLAGAGIV GLAVGFGAQG LVSDIVTGFF 
121:	ILLEKQLDVG DYITVSTFDG IVEQVGLRTT QIRSFDGTLH YIPNRNITNV SNHSRGTMQA 
181:	LVDIKVPAER NIDEMIHILQ QVCDETAAAL PQIKEGPNVI GIQELGTSEI VIRVIAKTEN 
241:	MEQWRVERVL RKEIKNAFDR AFPKETE