TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.24.1.11
Gap junction α-1 protein, GJα-1, Cx43, shf, sof, of 281 aas and 4 TMSs.  Can function both as a gap junction and a hemichannel and plays critical diverse roles in zebrafish bone growth (Misu et al. 2016).

Accession Number:O57474
Protein Name:Gap junction alpha-1 protein
Length:381
Molecular Weight:43455.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGDWSALGRL LDKVQAYSTA GGKVWLSVLF IFRILVLGTA VESAWGDEQS AFKCNTQQPG 
61:	CENVCYDKSF PISHVRFWVL QIIFVSTPTL LYLAHVFYLM RKEEKLNRKE EELKAVQNDG 
121:	GDVELHLKKI ELKKFKHGLE EHGKVKMKGS LLRTYIFSII FKSICEVVFL VIQWYLYGFS 
181:	LSAVYTCERT PCPHRVDCFL SRPTEKTIFI IFMLVVSLFS LLLNIIELFY VLFKRIKDRV 
241:	KSRQNTQFPT GTLSPTPKEL STTKYAYYNG CSSPTAPLSP MSPPGYKLAT GERTNSCRNY 
301:	NKQANEQNWA NYSTEQNRLG QNGSTISNSH AQAFDYPDDT HEHKKLTPGH ELQPLALIDA 
361:	RPCSRASSRM SSRARPDDLD V